Version 5.4
Homo sapiens Gene: RGS9BP
Summary
InnateDB Gene IDBG-42264.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol RGS9BP
Gene Name regulator of G protein signaling 9 binding protein
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000186326
Encoded Proteins
IDBP-42266
regulator of G protein signaling 9 binding protein
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The protein encoded by this gene functions as a regulator of G protein-coupled receptor signaling in phototransduction. Studies in bovine and mouse show that this gene is expressed only in the retina, and is localized in the rod outer segment membranes. This protein is associated with a heterotetrameric complex, specifically interacting with the regulator of G-protein signaling 9, and appears to function as the membrane anchor for the other largely soluble interacting partners. Mutations in this gene are associated with prolonged electroretinal response suppression (PERRS), also known as bradyopsia. [provided by RefSeq, Mar 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 19:32675407-32678300
Strand Forward strand
Band q13.11
Transcripts
ENST00000334176 ENSP00000334134
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
GO:0007603 phototransduction, visible light
GO:0009968 negative regulation of signal transduction
GO:0016056 rhodopsin mediated signaling pathway
GO:0022400 regulation of rhodopsin mediated signaling pathway
GO:0050908 detection of light stimulus involved in visual perception
Cellular Component
GO:0016021 integral component of membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000056043
View Gene Order
ENSBTAG00000039441
Not yet available
Pathways
NETPATH
REACTOME
REACT_111102
Signal Transduction pathway
REACT_160102
Diseases associated with visual transduction pathway
REACT_160125
Visual phototransduction pathway
REACT_163722
The phototransduction cascade pathway
REACT_163919
Inactivation, recovery and regulation of the phototransduction cascade pathway
REACT_116125
Disease pathway
KEGG
INOH
PID NCI
cone_pathway
Visual signal transduction: Cones
rhodopsin_pathway
Visual signal transduction: Rods
Cross-References
SwissProt Q6ZS82
TrEMBL
UniProt Splice Variant
Entrez Gene 388531
UniGene Hs.528491
RefSeq NM_207391
HUGO HGNC:30304
OMIM 607814
CCDS CCDS12424
HPRD
IMGT
EMBL AK124499 AK127646
GenPept BAC85865 BAC87072
RNA Seq Atlas 388531

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca