Version 5.4
Homo sapiens Gene: ATP10A
Summary
InnateDB Gene IDBG-4302.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ATP10A
Gene Name ATPase, class V, type 10A
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000206190
Encoded Proteins
IDBP-4304
ATPase, class V, type 10A
IDBP-4306
ATPase, class V, type 10A
IDBP-588145
ATPase, class V, type 10A
IDBP-599443
ATPase, class V, type 10A
IDBP-812451
ATPase, class V, type 10A
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The protein encoded by this gene belongs to the family of P-type cation transport ATPases, and to the subfamily of aminophospholipid-transporting ATPases. The aminophospholipid translocases transport phosphatidylserine and phosphatidylethanolamine from one side of a bilayer to another. This gene is maternally expressed. It maps within the most common interval of deletion responsible for Angelman syndrome, also known as 'happy puppet syndrome'. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 15:25677273-25865172
Strand Reverse strand
Band q12
Transcripts
ENST00000356865 ENSP00000349325
ENST00000389967 ENSP00000374617
ENST00000555815 ENSP00000450480
ENST00000555450
ENST00000555756 ENSP00000451615
ENST00000553577
ENST00000619904 ENSP00000480665
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 0
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0000166 nucleotide binding
GO:0000287 magnesium ion binding
GO:0004012 phospholipid-translocating ATPase activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0019829 cation-transporting ATPase activity
GO:0046872 metal ion binding
Biological Process
GO:0006812 cation transport
GO:0008152 metabolic process
GO:0008360 regulation of cell shape
GO:0015914 phospholipid transport
GO:0034220 ion transmembrane transport
GO:0045332 phospholipid translocation
GO:0055085 transmembrane transport
Cellular Component
GO:0005783 endoplasmic reticulum
GO:0005789 endoplasmic reticulum membrane
GO:0005886 plasma membrane
GO:0016021 integral component of membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000025324
View Gene Order
ENSBTAG00000027081
Not yet available
Pathways
NETPATH
REACTOME
REACT_25149
Ion transport by P-type ATPases pathway
REACT_15518
Transmembrane transport of small molecules pathway
REACT_25300
Ion channel transport pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.659258
RefSeq NM_024490 XM_005268261
HUGO
OMIM
CCDS CCDS32178
HPRD 05790
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca