Version 5.4
Homo sapiens Gene: NUDT7
Summary
InnateDB Gene IDBG-43024.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol NUDT7
Gene Name nudix (nucleoside diphosphate linked moiety X)-type motif 7
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000140876
Encoded Proteins
IDBP-43026
nudix (nucleoside diphosphate linked moiety X)-type motif 7
IDBP-381022
nudix (nucleoside diphosphate linked moiety X)-type motif 7
IDBP-752518
IDBP-753897
IDBP-750581
IDBP-812789
nudix (nucleoside diphosphate linked moiety X)-type motif 7
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The protein encoded by this gene is a member of the Nudix hydrolase family. Nudix hydrolases eliminate potentially toxic nucleotide metabolites from the cell and regulate the concentrations and availability of many different nucleotide substrates, cofactors, and signaling molecules. Alternatively spliced transcript variants encoding multiple isoforms have been found for this gene. [provided by RefSeq, Aug 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 16:77722492-77742260
Strand Forward strand
Band q23.1
Transcripts
ENST00000268533 ENSP00000268533
ENST00000437314 ENSP00000387707
ENST00000564031
ENST00000568787 ENSP00000456363
ENST00000563839 ENSP00000454617
ENST00000564085 ENSP00000457566
ENST00000613075 ENSP00000479582
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0000287 magnesium ion binding
GO:0003674 molecular_function
GO:0003986 acetyl-CoA hydrolase activity
GO:0005102 receptor binding
GO:0016787 hydrolase activity
GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
GO:0030145 manganese ion binding
GO:0030515 snoRNA binding
Biological Process
GO:0008150 biological_process
GO:0009132 nucleoside diphosphate metabolic process
GO:0015938 coenzyme A catabolic process
GO:0046356 acetyl-CoA catabolic process
GO:0050873 brown fat cell differentiation
Cellular Component
GO:0005777 peroxisome
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000031767
View Gene Order
ENSBTAG00000007184
Not yet available
Pathways
NETPATH
REACTOME
KEGG
hsa04146
Peroxisome pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.282665 Hs.741811
RefSeq NM_001105663 NM_001243657 NM_001243660 NM_001243661
HUGO
OMIM
CCDS CCDS42195 CCDS58479 CCDS58480 CCDS73916
HPRD
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca