Version 5.4
Homo sapiens Gene: TSPAN31
Summary
InnateDB Gene IDBG-43623.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TSPAN31
Gene Name tetraspanin 31
Synonyms SAS
Species Homo sapiens
Ensembl Gene ENSG00000135452
Encoded Proteins
IDBP-43625
tetraspanin 31
IDBP-601391
tetraspanin 31
IDBP-602822
tetraspanin 31
IDBP-589932
tetraspanin 31
IDBP-584072
tetraspanin 31
IDBP-584392
tetraspanin 31
IDBP-589088
tetraspanin 31
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is thought to be involved in growth-related cellular processes. This gene is associated with tumorigenesis and osteosarcoma. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 12:57738013-57750211
Strand Forward strand
Band q14.1
Transcripts
ENST00000257910 ENSP00000257910
ENST00000553221
ENST00000547311
ENST00000550528
ENST00000547992 ENSP00000448209
ENST00000552816 ENSP00000449312
ENST00000553089 ENSP00000446482
ENST00000549052 ENSP00000450195
ENST00000546993
ENST00000547472 ENSP00000449199
ENST00000548093
ENST00000548167 ENSP00000449131
ENST00000550791
ENST00000546922
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 0
Protein-DNA 0
Protein-RNA 1 [view]
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
GO:0008284 positive regulation of cell proliferation
Cellular Component
GO:0005887 integral component of plasma membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000006736
View Gene Order
ENSBTAG00000007158
Not yet available
Cross-References
SwissProt
TrEMBL F8VNT7
UniProt Splice Variant
Entrez Gene 6302
UniGene Hs.632708
RefSeq NM_005981 XM_005269074
HUGO HGNC:10539
OMIM 181035
CCDS CCDS8952
HPRD 01626
IMGT
EMBL AC025165
GenPept
RNA Seq Atlas 102724500 6302

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca