Version 5.4
Homo sapiens Gene: NUP160
Summary
InnateDB Gene IDBG-43974.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol NUP160
Gene Name nucleoporin 160kDa
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000030066
Encoded Proteins
IDBP-43976
nucleoporin 160kDa
IDBP-583702
nucleoporin 160kDa
IDBP-589555
nucleoporin 160kDa
IDBP-585462
nucleoporin 160kDa
IDBP-588085
nucleoporin 160kDa
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary NUP160 is 1 of up to 60 proteins that make up the 120-MD nuclear pore complex, which mediates nucleoplasmic transport.[supplied by OMIM, Apr 2004]
Gene Information
Type Protein coding
Genomic Location Chromosome 11:47778087-47848555
Strand Reverse strand
Band p11.2
Transcripts
ENST00000378460 ENSP00000367721
ENST00000530326 ENSP00000433590
ENST00000532773
ENST00000528071 ENSP00000432367
ENST00000526569
ENST00000527750
ENST00000528501 ENSP00000433964
ENST00000531016
ENST00000527126
ENST00000526870 ENSP00000431495
ENST00000529863
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 25 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 25 [view]
Protein-Protein 25 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005487 nucleocytoplasmic transporter activity
GO:0005515 protein binding
Biological Process
GO:0000278 mitotic cell cycle
GO:0005975 carbohydrate metabolic process
GO:0006406 mRNA export from nucleus
GO:0007077 mitotic nuclear envelope disassembly
GO:0008645 hexose transport
GO:0010827 regulation of glucose transport
GO:0015031 protein transport
GO:0015758 glucose transport
GO:0016032 viral process
GO:0019221 cytokine-mediated signaling pathway
GO:0044281 small molecule metabolic process
GO:0055085 transmembrane transport
Cellular Component
GO:0000776 kinetochore
GO:0005635 nuclear envelope
GO:0005643 nuclear pore
GO:0005829 cytosol
GO:0031080 nuclear pore outer ring
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000051329
View Gene Order
ENSBTAG00000021125
Not yet available
Pathways
NETPATH
REACTOME
REACT_150425
Resolution of Sister Chromatid Cohesion pathway
REACT_682
Mitotic Prometaphase pathway
REACT_150471
Separation of Sister Chromatids pathway
REACT_115831
ISG15 antiviral mechanism pathway
REACT_6804
Regulation of Glucokinase by Glucokinase Regulatory Protein pathway
REACT_212
Glucose transport pathway
REACT_9441
Hexose transport pathway
REACT_9395
Nuclear import of Rev protein pathway
REACT_7991
Vpr-mediated nuclear import of PICs pathway
REACT_6190
Rev-mediated nuclear export of HIV RNA pathway
REACT_6354
Viral Messenger RNA Synthesis pathway
REACT_6361
Late Phase of HIV Life Cycle pathway
REACT_15518
Transmembrane transport of small molecules pathway
REACT_6167
Influenza Infection pathway
REACT_6757
Interactions of Vpr with host cellular proteins pathway
REACT_200783
Myoclonic epilepsy of Lafora pathway
REACT_115676
Antiviral mechanism by IFN-stimulated genes pathway
REACT_75790
Cytokine Signaling in Immune system pathway
REACT_474
Metabolism of carbohydrates pathway
REACT_267668
Transcriptional regulation by small RNAs pathway
REACT_163931
Nuclear Pore Complex (NPC) Disassembly pathway
REACT_6152
Influenza Viral RNA Transcription and Replication pathway
REACT_25229
Interferon Signaling pathway
REACT_115566
Cell Cycle pathway
REACT_6900
Immune System pathway
REACT_910
M Phase pathway
REACT_6256
HIV Life Cycle pathway
REACT_1275
Mitotic Anaphase pathway
REACT_765
Mitotic Prophase pathway
REACT_152
Cell Cycle, Mitotic pathway
REACT_6185
HIV Infection pathway
REACT_6145
Influenza Life Cycle pathway
REACT_111217
Metabolism pathway
REACT_6288
Host Interactions of HIV factors pathway
REACT_19118
SLC-mediated transmembrane transport pathway
REACT_6916
Interactions of Rev with host cellular proteins pathway
REACT_71
Gene Expression pathway
REACT_160255
Nuclear Envelope Breakdown pathway
REACT_116125
Disease pathway
REACT_200833
Glycogen storage diseases pathway
REACT_150314
Mitotic Metaphase and Anaphase pathway
REACT_12472
Regulatory RNA pathways pathway
KEGG
hsa03013
RNA transport pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.643526 Hs.743599
RefSeq NM_015231 XM_006718170
HUGO
OMIM
CCDS CCDS31484
HPRD 16254
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca