Version 5.4
Homo sapiens Gene: HSPB6
Summary
InnateDB Gene IDBG-45272.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol HSPB6
Gene Name heat shock protein, alpha-crystallin-related, B6
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000004776
Encoded Proteins
IDBP-45274
heat shock protein, alpha-crystallin-related, B6
IDBP-765562
IDBP-760305
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This locus encodes a heat shock protein. The encoded protein likely plays a role in smooth muscle relaxation. [provided by RefSeq, Jan 2012]
Gene Information
Type Protein coding
Genomic Location Chromosome 19:35754568-35758079
Strand Reverse strand
Band q13.12
Transcripts
ENST00000004982 ENSP00000004982
ENST00000592984 ENSP00000468057
ENST00000587965 ENSP00000467169
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
Experimentally validated
Total 4 [view]
Protein-Protein 4 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005212 structural constituent of eye lens
GO:0005515 protein binding
GO:0042803 protein homodimerization activity
Biological Process
GO:0006937 regulation of muscle contraction
GO:0006950 response to stress
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000036854
View Gene Order
ENSBTAG00000018598
Not yet available
Cross-References
SwissProt O14558
TrEMBL V9HWB6
UniProt Splice Variant
Entrez Gene 126393
UniGene Hs.534538 Hs.706708 Hs.743506
RefSeq NM_144617
HUGO HGNC:26511
OMIM 610695
CCDS CCDS12475
HPRD 08130
IMGT
EMBL AC002398 AK056951 BC068046 EU794622
GenPept AAB81196 AAH68046 ACJ13676 BAB71323
RNA Seq Atlas 126393

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca