Homo sapiens Gene: ASB5
Summary
InnateDB Gene IDBG-45391.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ASB5
Gene Name ankyrin repeat and SOCS box containing 5
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000164122
Encoded Proteins
ankyrin repeat and SOCS box containing 5
ankyrin repeat and SOCS box containing 5
ankyrin repeat and SOCS box containing 5
Protein Structure
Entrez Gene
Summary The protein encoded by this gene is a member of the ankyrin repeat and SOCS box-containing (ASB) family of proteins. They contain ankyrin repeat sequence and SOCS box domain. The SOCS box serves to couple suppressor of cytokine signalling (SOCS) proteins and their binding partners with the elongin B and C complex, possibly targeting them for degradation. Multiple alternatively spliced transcript variants have been described for this gene but their full length sequences are not known. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 4:176213673-176277571
Strand Reverse strand
Band q34.2
Transcripts
ENST00000296525 ENSP00000296525
ENST00000512254 ENSP00000422877
ENST00000511879
ENST00000510578
ENST00000505299 ENSP00000423232
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 22 experimentally validated interaction(s) in this database.
Experimentally validated
Total 22 [view]
Protein-Protein 22 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0016567 protein ubiquitination
GO:0035556 intracellular signal transduction
Cellular Component
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
Non-SSD Ortholog
Possible paralog/unusual divergence/ gene prediction error
Not yet available
Non-SSD Ortholog
Possible paralog/unusual divergence/ gene prediction error
Pathways
NETPATH
REACTOME
Adaptive Immune System pathway
Immune System pathway
Antigen processing: Ubiquitination & Proteasome degradation pathway
Class I MHC mediated antigen processing & presentation pathway
KEGG
INOH
PID BIOCARTA
PID NCI
Cross-References
SwissProt Q8WWX0
TrEMBL D6R9Q2 Q5HYF3
UniProt Splice Variant
Entrez Gene 140458
UniGene Hs.352364 Hs.591712
RefSeq NM_080874 XM_005262759 XM_005262760
HUGO HGNC:17180
OMIM 615050
CCDS CCDS3827
HPRD 10672
IMGT
EMBL AC019163 AC093605 AK096441 AK098693 AY057053 BC065710 BX647857 CH471056
GenPept AAH65710 AAL18248 BAC04791 BAC05382 CAI46074 EAX04720
ImmGen ASB5 (murine)
RNA Seq Atlas 140458