Version 5.4
Homo sapiens Gene: ASB9
Summary
InnateDB Gene IDBG-45857.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ASB9
Gene Name ankyrin repeat and SOCS box containing 9
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000102048
Encoded Proteins
IDBP-45859
ankyrin repeat and SOCS box containing 9
IDBP-45861
ankyrin repeat and SOCS box containing 9
IDBP-45863
ankyrin repeat and SOCS box containing 9
IDBP-806672
ankyrin repeat and SOCS box containing 9
IDBP-598178
ankyrin repeat and SOCS box containing 9
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a member of the ankyrin repeat and suppressor of cytokine signaling (SOCS) box protein family. Members of this family can interact with the elongin B-C adapter complex via their SOCS box domain and further complex with the cullin and ring box proteins to form E3 ubiquitin ligase complexes. They may function to mediate the substrate-recognition of the E3 ubiquitin ligases. A transcribed pseudogene of this gene has been identified on chromosome 15. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome X:15235288-15270467
Strand Reverse strand
Band p22.2
Transcripts
ENST00000380488 ENSP00000369855
ENST00000380485 ENSP00000369852
ENST00000380483 ENSP00000369850
ENST00000477346 ENSP00000473542
ENST00000473862
ENST00000481384
ENST00000484017
ENST00000470015
ENST00000546332 ENSP00000438943
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 44 experimentally validated interaction(s) in this database.
Experimentally validated
Total 44 [view]
Protein-Protein 44 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0016567 protein ubiquitination
GO:0035556 intracellular signal transduction
GO:0045732 positive regulation of protein catabolic process
Cellular Component
GO:0005739 mitochondrion
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000031384
View Gene Order
ENSBTAG00000009198
Not yet available
Pathways
NETPATH
REACTOME
REACT_75842
Antigen processing: Ubiquitination & Proteasome degradation pathway
REACT_75774
Adaptive Immune System pathway
REACT_6900
Immune System pathway
REACT_75820
Class I MHC mediated antigen processing & presentation pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.19404 Hs.717671
RefSeq NM_001031739 NM_001168530 NM_001168531 NM_024087 XM_005274446 XM_005274448
HUGO
OMIM
CCDS CCDS14163 CCDS35208 CCDS55372
HPRD 06452
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca