Version 5.4
| Homo sapiens Gene: CLDN24 | |||||||
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| Summary | |||||||
| InnateDB Gene | IDBG-45950.6 | ||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||
| Gene Symbol | CLDN24 | ||||||
| Gene Name | claudin 24 | ||||||
| Synonyms | |||||||
| Species | Homo sapiens | ||||||
| Ensembl Gene | ENSG00000185758 | ||||||
| Encoded Proteins |
claudin 24
claudin 24
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| Protein Structure |
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| Useful resources | Stemformatics EHFPI ImmGen | ||||||
| Entrez Gene | |||||||
| Summary |
This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. The protein encoded by this gene is 75% identical to the mouse homolog. This gene is upstream of the CLDN22 gene, which overlaps the WWC2 gene on the opposite strand in the genome.[provided by RefSeq, Aug 2010] |
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| Gene Information | |||||||
| Type | Protein coding | ||||||
| Genomic Location | Chromosome 4:183321764-183322426 | ||||||
| Strand | Reverse strand | ||||||
| Band | q35.1 | ||||||
| Transcripts |
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| Interactions | |||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
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| Gene Ontology | |||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Orthologs | |||||||
| No orthologs found for this gene | |||||||
| Pathways | |||||||
| NETPATH | |||||||
| REACTOME | |||||||
| KEGG |
Cell adhesion molecules (CAMs) pathway
Leukocyte transendothelial migration pathway
Tight junction pathway
Hepatitis C pathway
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| INOH | |||||||
| PID NCI | |||||||
| Cross-References | |||||||
| SwissProt | A6NM45 | ||||||
| TrEMBL | D6RBY1 | ||||||
| UniProt Splice Variant | |||||||
| Entrez Gene | 100132463 | ||||||
| UniGene | Hs.727475 | ||||||
| RefSeq | NM_001185149 | ||||||
| HUGO | HGNC:37200 | ||||||
| OMIM | |||||||
| CCDS | CCDS54824 | ||||||
| HPRD | |||||||
| IMGT | |||||||
| EMBL | AC093844 | ||||||
| GenPept | |||||||
| RNA Seq Atlas | 100132463 | ||||||