Version 5.4
Homo sapiens Gene: GALM
Summary
InnateDB Gene IDBG-46608.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol GALM
Gene Name galactose mutarotase (aldose 1-epimerase)
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000143891
Encoded Proteins
IDBP-46612
galactose mutarotase (aldose 1-epimerase)
IDBP-293966
galactose mutarotase (aldose 1-epimerase)
IDBP-373001
galactose mutarotase (aldose 1-epimerase)
IDBP-373011
galactose mutarotase (aldose 1-epimerase)
IDBP-373012
galactose mutarotase (aldose 1-epimerase)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes an enzyme that catalyzes the epimerization of hexose sugars such as glucose and galactose. The encoded protein is expressed in the cytoplasm and has a preference for galactose. The encoded protein may be required for normal galactose metabolism by maintaining the equilibrium of alpha and beta anomers of galactose.[provided by RefSeq, Mar 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome 2:38665910-38741237
Strand Forward strand
Band p22.1
Transcripts
ENST00000272252 ENSP00000272252
ENST00000410063 ENSP00000386233
ENST00000427858 ENSP00000410598
ENST00000444351 ENSP00000409083
ENST00000434934 ENSP00000399473
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0003824 catalytic activity
GO:0004034 aldose 1-epimerase activity
GO:0016853 isomerase activity
GO:0030246 carbohydrate binding
Biological Process
GO:0005975 carbohydrate metabolic process
GO:0006006 glucose metabolic process
GO:0006012 galactose metabolic process
Cellular Component
GO:0005737 cytoplasm
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000035473
View Gene Order
ENSBTAG00000021102
Not yet available
Pathways
NETPATH
REACTOME
KEGG
hsa00052
Galactose metabolism pathway
hsa00010
Glycolysis / Gluconeogenesis pathway
INOH
PID NCI
Cross-References
SwissProt Q96C23
TrEMBL B8ZZ75 F8WB82 H7C1B5 H7C320
UniProt Splice Variant
Entrez Gene 130589
UniGene Hs.435012 Hs.596752
RefSeq NM_138801
HUGO HGNC:24063
OMIM 608883
CCDS CCDS1797
HPRD
IMGT
EMBL AC074366 AK291489 AY064378 AY064379 AY064380 AY064381 AY064382 AY064383 AY064384 AY064385 BC014916 BC019263 CH471053 EU794611
GenPept AAH14916 AAH19263 AAL62475 AAL62476 AAX93101 ACJ13665 BAF84178 EAX00367
RNA Seq Atlas 130589

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca