Version 5.4
Homo sapiens Gene: NIT2
Summary
InnateDB Gene IDBG-47288.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol NIT2
Gene Name nitrilase family, member 2
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000114021
Encoded Proteins
IDBP-242214
nitrilase family, member 2
IDBP-477780
nitrilase family, member 2
IDBP-482444
nitrilase family, member 2
IDBP-485365
nitrilase family, member 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 3:100334701-100356866
Strand Forward strand
Band q12.2
Transcripts
ENST00000394140 ENSP00000377696
ENST00000465368
ENST00000478856
ENST00000480073 ENSP00000419157
ENST00000460317 ENSP00000419239
ENST00000497785 ENSP00000419189
ENST00000472392
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 15 experimentally validated interaction(s) in this database.
Experimentally validated
Total 15 [view]
Protein-Protein 15 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds
GO:0050152 omega-amidase activity
Biological Process
GO:0006107 oxaloacetate metabolic process
GO:0006528 asparagine metabolic process
GO:0006541 glutamine metabolic process
GO:0006807 nitrogen compound metabolic process
Cellular Component
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0005813 centrosome
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000022751
View Gene Order
ENSBTAG00000004833
Not yet available
Pathways
NETPATH
REACTOME
KEGG
hsa00250
Alanine, aspartate and glutamate metabolism pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.439152 Hs.604432
RefSeq NM_020202
HUGO
OMIM
CCDS CCDS33806
HPRD 17634
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca