Homo sapiens Gene: CYP4V2
Summary
InnateDB Gene IDBG-47438.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CYP4V2
Gene Name cytochrome P450, family 4, subfamily V, polypeptide 2
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000145476
Encoded Proteins
cytochrome P450, family 4, subfamily V, polypeptide 2
Protein Structure
Entrez Gene
Summary This gene encodes a member of the cytochrome P450 hemethiolate protein superfamily which are involved in oxidizing various substrates in the metabolic pathway. It is implicated in the metabolism of fatty acid precursors into n-3 polyunsaturated fatty acids. Mutations in this gene result in Bietti crystalline corneoretinal dystrophy. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 4:186191520-186213456
Strand Forward strand
Band q35.1
Transcripts
ENST00000378802 ENSP00000368079
ENST00000507209
ENST00000513354
ENST00000502665
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
Experimentally validated
Total 3 [view]
Protein-Protein 3 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004497 monooxygenase activity
GO:0005506 iron ion binding
GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
GO:0020037 heme binding
Biological Process
GO:0007601 visual perception
GO:0010430 fatty acid omega-oxidation
GO:0050896 response to stimulus
GO:0055114 oxidation-reduction process
Cellular Component
GO:0005789 endoplasmic reticulum membrane
GO:0016021 integral component of membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
SSD Ortholog
Ortholog supports species divergence
Not yet available
SSD Ortholog
Ortholog supports species divergence
Cross-References
SwissProt Q6ZWL3
TrEMBL Q49AA5
UniProt Splice Variant
Entrez Gene 285440
UniGene Hs.587231
RefSeq NM_207352 XM_005262935
HUGO HGNC:23198
OMIM 608614
CCDS CCDS34119
HPRD 16777
IMGT
EMBL AC110771 AK122600 AK126473 AY422002 BC041839 BC060857 FJ440682
GenPept AAH41839 AAH60857 AAR31180 ACK44069 BAC85487 BAC86562
ImmGen CYP4V2 (murine)
RNA Seq Atlas 285440