Homo sapiens Gene: CYP4V2

Summary
InnateDB Gene IDBG-47438.5
Last Modified 2012-02-14   [Report errors or provide feedback]
Gene Symbol CYP4V2
Gene Name cytochrome P450, family 4, subfamily V, polypeptide 2
Synonyms BCD; CYP4AH1
Species Homo sapiens
Ensembl Gene ENSG00000145476
Encoded Proteins
IDBP-47440 cytochrome P450, family 4, subfamily V, polypeptide 2
Entrez Gene
Summary This gene encodes a member of the cytochrome P450 hemethiolate protein superfamily which are involved in oxidizing various substrates in the metabolic pathway. It is implicated in the metabolism of fatty acid precursors into n-3 polyunsaturated fatty acids. Mutations in this gene result in Bietti crystalline corneoretinal dystrophy. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 4: 187112674-187134610
Strand Forward strand
Band q35.2
Transcripts
ENST00000378802  ENSP00000368079
ENST00000507209 
ENST00000513354 
ENST00000502665 
Interactions
Number of Interactions   This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
Experimentally validated
Total 3 [view]
Protein‑Protein  3
[view]
Protein‑DNA 0
Protein‑RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
 
Gene Ontology
Accession GO Term
Molecular Function
GO:0004497 monooxygenase activity
GO:0005506 iron ion binding
GO:0009055 electron carrier activity
GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
GO:0020037 heme binding
Biological Process
GO:0007601 visual perception
GO:0010430 fatty acid omega-oxidation
GO:0050896 response to stimulus
GO:0055114 oxidation-reduction process
Cellular Component
GO:0005789 endoplasmic reticulum membrane
GO:0016021 integral to membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID Gene Order Method Confidence Comments
ENSMUSG00000079057 Ortholuge SSD Ortholog Ortholog supports species divergence
ENSBTAG00000021263 Not yet available Ortholuge SSD Ortholog Ortholog supports species divergence
Pathways
NETPATH
REACTOME
KEGG
INOH
PID BIOCARTA
PID NCI
Cross-References
SwissProt Q6ZWL3 
TrEMBL Q49AA5
UniProt Splice Variant
Entrez Gene 285440 
UniGene Hs.587231
RefSeq NM_207352 
HUGO 23198 
OMIM 608614
CCDS CCDS34119 
HPRD 16777
IMGT
EMBL AC110771 AK122600 AK126473 AY422002 BC041839 BC060857 FJ440682
GenPept AAH41839  AAH60857  AAR31180  ACK44069  BAC85487  BAC86562 
ImmGen CYP4V2 (murine) 
RNA Seq Atlas 285440