Version 5.4
Homo sapiens Gene: ZNF746
Summary
InnateDB Gene IDBG-47452.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ZNF746
Gene Name zinc finger protein 746
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000181220
Encoded Proteins
IDBP-47454
zinc finger protein 746
IDBP-387239
zinc finger protein 746
IDBP-475200
zinc finger protein 746
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 7:149472794-149497817
Strand Reverse strand
Band q36.1
Transcripts
ENST00000340622 ENSP00000345140
ENST00000458143 ENSP00000395007
ENST00000471735
ENST00000461958 ENSP00000420329
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 28 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 28 [view]
Protein-Protein 27 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003676 nucleic acid binding
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0005515 protein binding
GO:0031625 ubiquitin protein ligase binding
GO:0044212 transcription regulatory region DNA binding
GO:0046872 metal ion binding
Biological Process
GO:0000122 negative regulation of transcription from RNA polymerase II promoter
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0010941 regulation of cell death
GO:0045892 negative regulation of transcription, DNA-templated
GO:0045944 positive regulation of transcription from RNA polymerase II promoter
GO:0070997 neuron death
Cellular Component
GO:0005622 intracellular
GO:0005634 nucleus
GO:0005737 cytoplasm
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000057691
View Gene Order
ENSBTAG00000031106
Not yet available
Pathways
NETPATH
REACTOME
REACT_12627
Generic Transcription Pathway pathway
REACT_71
Gene Expression pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt Q6NUN9
TrEMBL Q96N48
UniProt Splice Variant
Entrez Gene 155061
UniGene Hs.24643 Hs.695426
RefSeq NM_001163474 NM_152557
HUGO HGNC:21948
OMIM 613914
CCDS CCDS55180 CCDS5897
HPRD 08099
IMGT
EMBL AC073314 AK055975 AK128244 AK291814 BC068505
GenPept AAH68505 BAB71061 BAC87351 BAF84503
RNA Seq Atlas 155061

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca