Version 5.4
Homo sapiens Gene: IMPG2
Summary
InnateDB Gene IDBG-47660.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol IMPG2
Gene Name interphotoreceptor matrix proteoglycan 2
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000081148
Encoded Proteins
IDBP-47662
interphotoreceptor matrix proteoglycan 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The protein encoded by this gene binds chondroitin sulfate and hyaluronan and is a proteoglycan. The encoded protein plays a role in the organization of the interphotoreceptor matrix and may promote the growth and maintenance of the light-sensitive photoreceptor outer segment. Defects in this gene are a cause of retinitis pigmentosa type 56 and maculopathy, IMPG2-related.[provided by RefSeq, Mar 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 3:101222546-101320560
Strand Reverse strand
Band q12.3
Transcripts
ENST00000193391 ENSP00000193391
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005201 extracellular matrix structural constituent
GO:0005515 protein binding
GO:0005540 hyaluronic acid binding
GO:0008201 heparin binding
Biological Process
GO:0007601 visual perception
Cellular Component
GO:0005578 proteinaceous extracellular matrix
GO:0016021 integral component of membrane
GO:0043235 receptor complex
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000035270
View Gene Order
ENSBTAG00000015662
Not yet available
Cross-References
SwissProt Q9BZV3
TrEMBL F1T0J3
UniProt Splice Variant
Entrez Gene 50939
UniGene Hs.209249
RefSeq NM_016247
HUGO HGNC:18362
OMIM 607056
CCDS CCDS2940
HPRD
IMGT
EMBL AB593127 AC068764 AF157624 AF173155 AF271363 AF271364 AF271365 AF271366 AF271367 AF271368 AF271369 AF271370 AF271371 AF271372 AF271373 AF271374 AF271375 AF271376 AF271377 AF271378 AF271379
GenPept AAF06999 AAF13154 AAG49889 BAJ84067
RNA Seq Atlas 50939

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca