Version 5.4
Homo sapiens Gene: OR5B12
Summary
InnateDB Gene IDBG-47705.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol OR5B12
Gene Name olfactory receptor, family 5, subfamily B, member 12
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000172362
Encoded Proteins
IDBP-47707
olfactory receptor, family 5, subfamily B, member 12
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 11:58439120-58440173
Strand Reverse strand
Band q12.1
Transcripts
ENST00000302572 ENSP00000306657
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0004930 G-protein coupled receptor activity
GO:0004984 olfactory receptor activity
Biological Process
GO:0007186 G-protein coupled receptor signaling pathway
GO:0050911 detection of chemical stimulus involved in sensory perception of smell
Cellular Component
GO:0005886 plasma membrane
GO:0016021 integral component of membrane
Orthologs
No orthologs found for this gene
Pathways
NETPATH
REACTOME
REACT_15488
Olfactory Signaling Pathway pathway
REACT_14797
Signaling by GPCR pathway
REACT_111102
Signal Transduction pathway
REACT_19184
GPCR downstream signaling pathway
KEGG
hsa04740
Olfactory transduction pathway
INOH
PID NCI
Cross-References
SwissProt Q96R08
TrEMBL
UniProt Splice Variant
Entrez Gene 390191
UniGene Hs.553754
RefSeq NM_001004733
HUGO HGNC:15432
OMIM
CCDS CCDS31551
HPRD
IMGT
EMBL AB065851 AF399637 BC136947 BC136948 BK004507 CH471076
GenPept AAI36948 AAI36949 AAK95122 BAC06069 DAA04905 EAW73806
RNA Seq Atlas 390191

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca