Version 5.4
Homo sapiens Gene: MZB1
Summary
InnateDB Gene IDBG-47792.7
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol MZB1
Gene Name marginal zone B and B1 cell-specific protein
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000170476
Encoded Proteins
IDBP-47794
Plasma cell-induced resident endoplasmic reticulum protein
IDBP-377991
Plasma cell-induced resident endoplasmic reticulum protein
IDBP-481994
Plasma cell-induced resident endoplasmic reticulum protein
IDBP-477283
Plasma cell-induced resident endoplasmic reticulum protein
IDBP-479061
Plasma cell-induced resident endoplasmic reticulum protein
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 5:139387480-139390081
Strand Reverse strand
Band q31.2
Transcripts
ENST00000302125 ENSP00000303920
ENST00000417694 ENSP00000415420
ENST00000503481 ENSP00000423205
ENST00000513389 ENSP00000425850
ENST00000503120
ENST00000511979
ENST00000503351 ENSP00000424481
ENST00000509591
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Experimentally validated
Total 3 [view]
Protein-Protein 3 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0002642 positive regulation of immunoglobulin biosynthetic process
GO:0006915 apoptotic process
GO:0008284 positive regulation of cell proliferation
GO:0030888 regulation of B cell proliferation
GO:0033622 integrin activation
GO:0042127 regulation of cell proliferation
GO:2001274 negative regulation of glucose import in response to insulin stimulus
Cellular Component
GO:0005576 extracellular region
GO:0005737 cytoplasm
GO:0005788 endoplasmic reticulum lumen
GO:0034663 endoplasmic reticulum chaperone complex
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000024353
View Gene Order
ENSBTAG00000038337
Not yet available
Cross-References
SwissProt Q8WU39
TrEMBL
UniProt Splice Variant
Entrez Gene 51237
UniGene
RefSeq NM_016459
HUGO HGNC:30125
OMIM 609447
CCDS CCDS47273
HPRD 17815
IMGT
EMBL AC135457 AF151024 AF338109 AK292706 AL698690 BC009931 BC021275 BP366737 GQ477350
GenPept AAF36110 AAH09931 AAH21275 AAK84085 ACY74343 BAF85395
RNA Seq Atlas 51237

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca