Version 5.4
Homo sapiens Gene: KRT25
Summary
InnateDB Gene IDBG-48040.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol KRT25
Gene Name keratin 25
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000204897
Encoded Proteins
IDBP-48042
keratin 25
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a member of the type I (acidic) keratin family, which belongs to the superfamily of intermediate filament (IF) proteins. Keratins are heteropolymeric structural proteins which form the intermediate filament. These filaments, along with actin microfilaments and microtubules, compose the cytoskeleton of epithelial cells. The type I keratin genes are clustered in a region of chromosome 17q12-q21. [provided by RefSeq, Jul 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome 17:40748021-40755332
Strand Reverse strand
Band q21.2
Transcripts
ENST00000312150 ENSP00000310573
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0005198 structural molecule activity
GO:0005515 protein binding
Biological Process
GO:0007568 aging
GO:0031069 hair follicle morphogenesis
GO:0042633 hair cycle
GO:0045109 intermediate filament organization
Cellular Component
GO:0005575 cellular_component
GO:0005737 cytoplasm
GO:0005882 intermediate filament
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000035831
View Gene Order
ENSBTAG00000030542
Not yet available
Cross-References
SwissProt Q7Z3Z0
TrEMBL
UniProt Splice Variant
Entrez Gene 147183
UniGene Hs.55412
RefSeq NM_181534
HUGO HGNC:30839
OMIM
CCDS CCDS11373
HPRD
IMGT
EMBL AJ564204 CH471152
GenPept CAD91904 EAW60676
RNA Seq Atlas 147183

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca