Homo sapiens Gene: PRDM7
Summary
InnateDB Gene IDBG-49018.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PRDM7
Gene Name PR domain containing 7
Synonyms PFM4; ZNF910
Species Homo sapiens
Ensembl Gene ENSG00000126856
Encoded Proteins
PR domain containing 7
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The protein encoded by this gene is a transcription factor of the PR-domain protein family. It contains a PR-domain and multiple zinc finger motifs. Transcription factors of the PR-domain family are known to be involved in cell differentiation and tumorigenesis. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008]
This gene encodes a member of a family of proteins that may have roles in transcription and other nuclear processes. The encoded protein contains a KRAB (Kruppel-associated box) domain -A box and a SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain and may function as a histone methyltransferase. [provided by RefSeq, Aug 2013]
Gene Information
Type Protein coding
Genomic Location Chromosome 16:90056566-90092072
Strand Reverse strand
Band q24.3
Transcripts
ENST00000325921
ENST00000449207 ENSP00000396732
ENST00000568473 ENSP00000455390
ENST00000564210 ENSP00000457667
ENST00000569206
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003676 nucleic acid binding
GO:0005515 protein binding
GO:0018024 histone-lysine N-methyltransferase activity
Biological Process
GO:0006355 regulation of transcription, DNA-templated
GO:0034968 histone lysine methylation
Cellular Component
GO:0005622 intracellular
GO:0005634 nucleus
GO:0005694 chromosome
Orthologs
No orthologs found for this gene
Pathways
NETPATH
REACTOME
Generic Transcription Pathway pathway
Gene Expression pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.406695
RefSeq NM_001098173 XM_005256274
HUGO
OMIM
CCDS CCDS45557
HPRD 17903
IMGT
EMBL
GenPept
RNA Seq Atlas