Version 5.4
Homo sapiens Gene: FBXO15
Summary
InnateDB Gene IDBG-4903.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol FBXO15
Gene Name F-box protein 15
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000141665
Encoded Proteins
IDBP-372412
F-box protein 15
IDBP-725749
IDBP-725971
IDBP-726771
IDBP-726448
IDBP-727600
IDBP-725673
IDBP-726963
IDBP-727179
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Members of the F-box protein family, such as FBXO15, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]).[supplied by OMIM, Mar 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 18:74073353-74147865
Strand Reverse strand
Band q22.3
Transcripts
ENST00000419743 ENSP00000393154
ENST00000579517 ENSP00000463247
ENST00000584425
ENST00000583443 ENSP00000464177
ENST00000582526 ENSP00000463529
ENST00000578399 ENSP00000462151
ENST00000585174 ENSP00000463378
ENST00000579108
ENST00000580552 ENSP00000462361
ENST00000580806
ENST00000580088 ENSP00000462117
ENST00000581214 ENSP00000462143
ENST00000577575
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.
Experimentally validated
Total 4 [view]
Protein-Protein 4 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 6 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
Cellular Component
GO:0019005 SCF ubiquitin ligase complex
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000034391
View Gene Order
ENSBTAG00000009686
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.664011 Hs.734532
RefSeq NM_001142958 NM_152676 XM_006722416
HUGO
OMIM
CCDS CCDS45884
HPRD 16435
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca