Version 5.4
Homo sapiens Gene: CD96
Summary
InnateDB Gene IDBG-49394.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CD96
Gene Name CD96 molecule
Synonyms TACTILE
Species Homo sapiens
Ensembl Gene ENSG00000153283
Encoded Proteins
IDBP-49396
CD96 molecule
IDBP-49398
CD96 molecule
IDBP-382325
CD96 molecule
IDBP-478702
CD96 molecule
IDBP-484934
CD96 molecule
IDBP-485287
CD96 molecule
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The protein encoded by this gene belongs to the immunoglobulin superfamily. It is a type I membrane protein. The protein may play a role in the adhesive interactions of activated T and NK cells during the late phase of the immune response. It may also function in antigen presentation. Alternative splicing occurs at this locus and two transcript variants encoding distinct isoforms have been identified. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 3:111292719-111665750
Strand Forward strand
Band q13.13
Transcripts
ENST00000283285 ENSP00000283285
ENST00000352690 ENSP00000342040
ENST00000438817 ENSP00000389801
ENST00000488054 ENSP00000417680
ENST00000494798 ENSP00000417152
ENST00000465428 ENSP00000417150
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0006955 immune response
GO:0007155 cell adhesion
GO:0050776 regulation of immune response
Cellular Component
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000022657
View Gene Order
ENSBTAG00000014441
Not yet available
Pathways
NETPATH
REACTOME
REACT_11152
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell pathway
REACT_75774
Adaptive Immune System pathway
REACT_6900
Immune System pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene 10225
UniGene Hs.142023
RefSeq NM_005816 NM_198196 XM_005247063 XM_006713469 XM_006713470
HUGO HGNC:16892
OMIM 606037
CCDS CCDS2958 CCDS2959
HPRD 06916
IMGT
EMBL
GenPept
RNA Seq Atlas 10225

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca