Version 5.4
Homo sapiens Gene: CAPN12
Summary
InnateDB Gene IDBG-49442.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CAPN12
Gene Name calpain 12
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000182472
Encoded Proteins
IDBP-49444
calpain 12
IDBP-766121
IDBP-766238
IDBP-763605
IDBP-760045
IDBP-765459
IDBP-765950
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The calpains, calcium-activated neutral proteases, are nonlysosomal, intracellular cysteine proteases. The mammalian calpains include ubiquitous, stomach-specific, and muscle-specific proteins. The ubiquitous enzymes consist of heterodimers with distinct large, catalytic subunits associated with a common small, regulatory subunit. This gene encodes a member of the calpain large subunit family. [provided by RefSeq, Jun 2012]
Gene Information
Type Protein coding
Genomic Location Chromosome 19:38730187-38769904
Strand Reverse strand
Band q13.2
Transcripts
ENST00000328867 ENSP00000331636
ENST00000598684 ENSP00000470233
ENST00000594552 ENSP00000469217
ENST00000597716
ENST00000601685
ENST00000597354
ENST00000597987 ENSP00000470760
ENST00000595177 ENSP00000471007
ENST00000594497
ENST00000593700
ENST00000597740 ENSP00000471510
ENST00000601953 ENSP00000473156
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0004198 calcium-dependent cysteine-type endopeptidase activity
GO:0005509 calcium ion binding
Biological Process
GO:0006508 proteolysis
Cellular Component
GO:0005622 intracellular
GO:0005737 cytoplasm
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000054083
View Gene Order
ENSBTAG00000013239
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.731775
RefSeq NM_144691
HUGO
OMIM
CCDS CCDS12519
HPRD 07007
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca