Version 5.4
| Homo sapiens Gene: PCDHB1 | |||||||
|---|---|---|---|---|---|---|---|
| Summary | |||||||
| InnateDB Gene | IDBG-49838.6 | ||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||
| Gene Symbol | PCDHB1 | ||||||
| Gene Name | protocadherin beta 1 | ||||||
| Synonyms | |||||||
| Species | Homo sapiens | ||||||
| Ensembl Gene | ENSG00000171815 | ||||||
| Encoded Proteins |
protocadherin beta 1
|
||||||
| Protein Structure |
|
||||||
| Useful resources | Stemformatics EHFPI ImmGen | ||||||
| Entrez Gene | |||||||
| Summary |
This gene is a member of the protocadherin beta gene cluster, one of three related gene clusters tandemly linked on chromosome five. The gene clusters demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The beta cluster contains 16 genes and 3 pseudogenes, each encoding 6 extracellular cadherin domains and a cytoplasmic tail that deviates from others in the cadherin superfamily. The extracellular domains interact in a homophilic manner to specify differential cell-cell connections. Unlike the alpha and gamma clusters, the transcripts from these genes are made up of only one large exon, not sharing common 3' exons as expected. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins. Their specific functions are unknown but they most likely play a critical role in the establishment and function of specific cell-cell neural connections. [provided by RefSeq, Jul 2008] |
||||||
| Gene Information | |||||||
| Type | Protein coding | ||||||
| Genomic Location | Chromosome 5:141051135-141059344 | ||||||
| Strand | Forward strand | ||||||
| Band | q31.3 | ||||||
| Transcripts |
|
||||||
| Interactions | |||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
|
||||||
| Gene Ontology | |||||||
Molecular Function |
|
||||||
| Biological Process |
|
||||||
| Cellular Component |
|
||||||
| Orthologs | |||||||
|
Species
Mus musculus
Bos taurus
|
Gene ID
Gene Order
Not yet available
|
||||||
| Cross-References | |||||||
| SwissProt | Q9Y5F3 | ||||||
| TrEMBL | |||||||
| UniProt Splice Variant | |||||||
| Entrez Gene | 29930 | ||||||
| UniGene | Hs.278950 | ||||||
| RefSeq | NM_013340 | ||||||
| HUGO | HGNC:8680 | ||||||
| OMIM | 606327 | ||||||
| CCDS | CCDS4243 | ||||||
| HPRD | 08397 | ||||||
| IMGT | |||||||
| EMBL | AF152488 BC112096 BC112098 CH471062 | ||||||
| GenPept | AAD43749 AAI12097 AAI12099 EAW61985 | ||||||
| RNA Seq Atlas | 29930 | ||||||