Version 5.4
Homo sapiens Gene: FKBP10
Summary
InnateDB Gene IDBG-49851.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol FKBP10
Gene Name FK506 binding protein 10, 65 kDa
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000141756
Encoded Proteins
IDBP-49853
FK506 binding protein 10, 65 kDa
IDBP-378289
FK506 binding protein 10, 65 kDa
IDBP-378298
FK506 binding protein 10, 65 kDa
IDBP-759920
IDBP-763695
IDBP-763195
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The protein encoded by this gene belongs to the FKBP-type peptidyl-prolyl cis/trans isomerase (PPIase) family. This protein localizes to the endoplasmic reticulum and acts as a molecular chaperone. Alternatively spliced variants encoding different isoforms have been reported, but their biological validity has not been determined.[provided by RefSeq, Nov 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome 17:41812680-41823217
Strand Forward strand
Band q21.2
Transcripts
ENST00000321562 ENSP00000317232
ENST00000429461 ENSP00000408232
ENST00000455106 ENSP00000416822
ENST00000489591 ENSP00000466352
ENST00000487489
ENST00000490938
ENST00000464180
ENST00000585922 ENSP00000466097
ENST00000585664 ENSP00000468703
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 20 experimentally validated interaction(s) in this database.
Experimentally validated
Total 20 [view]
Protein-Protein 19 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003755 peptidyl-prolyl cis-trans isomerase activity
GO:0005509 calcium ion binding
GO:0005515 protein binding
GO:0005528 FK506 binding
Biological Process
GO:0000413 protein peptidyl-prolyl isomerization
GO:0006457 protein folding
GO:0061077 chaperone-mediated protein folding
Cellular Component
GO:0005788 endoplasmic reticulum lumen
GO:0005789 endoplasmic reticulum membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000001555
View Gene Order
ENSBTAG00000011454
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.463035 Hs.602552 Hs.694714
RefSeq NM_021939
HUGO
OMIM
CCDS CCDS11409
HPRD 09522
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca