Homo sapiens Gene: SDHAF2
Summary
InnateDB Gene IDBG-50166.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SDHAF2
Gene Name succinate dehydrogenase complex assembly factor 2
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000167985
Encoded Proteins
succinate dehydrogenase complex assembly factor 2
succinate dehydrogenase complex assembly factor 2
succinate dehydrogenase complex assembly factor 2
succinate dehydrogenase complex assembly factor 2
Protein Structure
Entrez Gene
Summary This gene encodes a mitochondrial protein needed for the flavination of a succinate dehydrogenase complex subunit required for activity of the complex. Mutations in this gene are associated with paraganglioma.[provided by RefSeq, Jul 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 11:61430042-61447529
Strand Forward strand
Band q12.2
Transcripts
ENST00000301761 ENSP00000301761
ENST00000359614 ENSP00000352630
ENST00000542794 ENSP00000439983
ENST00000542074 ENSP00000469670
ENST00000534878 ENSP00000471030
ENST00000537782 ENSP00000469951
ENST00000536250 ENSP00000471120
ENST00000543265 ENSP00000443660
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 19 experimentally validated interaction(s) in this database.
Experimentally validated
Total 19 [view]
Protein-Protein 19 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0006121 mitochondrial electron transport, succinate to ubiquinone
GO:0006470 protein dephosphorylation
GO:0010719 negative regulation of epithelial to mesenchymal transition
GO:0018293 protein-FAD linkage
GO:0090090 negative regulation of canonical Wnt signaling pathway
Cellular Component
GO:0005739 mitochondrion
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
Non-SSD Ortholog
Possible paralog/unusual divergence/ gene prediction error
Not yet available
Non-SSD Ortholog
Possible paralog/unusual divergence/ gene prediction error
Cross-References
SwissProt Q9NX18
TrEMBL F5GYJ5 F5H4T4 F5H8E2 F8W679 M0QY91 M0QYN2 M0R060
UniProt Splice Variant
Entrez Gene 54949
UniGene Hs.609629
RefSeq NM_017841
HUGO HGNC:26034
OMIM 613019
CCDS CCDS8007
HPRD 07915
IMGT
EMBL AK000494 AP003108 BC002331
GenPept AAH02331 BAA91204
ImmGen SDHAF2 (murine)
RNA Seq Atlas 54949