Version 5.4
| Homo sapiens Gene: SCGB1D1 | |||||
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| Summary | |||||
| InnateDB Gene | IDBG-50837.6 | ||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||
| Gene Symbol | SCGB1D1 | ||||
| Gene Name | secretoglobin, family 1D, member 1 | ||||
| Synonyms | LIPA; LPHA; LPNA | ||||
| Species | Homo sapiens | ||||
| Ensembl Gene | ENSG00000168515 | ||||
| Encoded Proteins |
secretoglobin, family 1D, member 1
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| Protein Structure |
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| Useful resources | Stemformatics EHFPI ImmGen | ||||
| Entrez Gene | |||||
| Summary |
The protein encoded by this gene is a member of the lipophilin subfamily, part of the uteroglobin superfamily, and is an ortholog of prostatein, the major secretory glycoprotein of the rat ventral prostate gland. This gene product represents one component of a heterodimeric molecule present in human tears whose elution profile is consistent with prostatein, a tetrameric molecule composed of three peptide components in heterodimers. Assuming that human lipophilins are the functional counterparts of prostatein, they may be transcriptionally regulated by steroid hormones, with the ability to bind androgens, other steroids and possibly bind and concentrate estramustine, a chemotherapeutic agent widely used for prostate cancer. Although the gene has been reported to be on chromosome 15, this sequence appears to be from a cluster of genes on chromosome 11 that includes mammaglobin 2. [provided by RefSeq, Jul 2008] |
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| Gene Information | |||||
| Type | Protein coding | ||||
| Genomic Location | Chromosome 11:62190216-62193539 | ||||
| Strand | Forward strand | ||||
| Band | q12.3 | ||||
| Transcripts |
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| Interactions | |||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
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| Gene Ontology | |||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Orthologs | |||||
| No orthologs found for this gene | |||||
| Cross-References | |||||
| SwissProt | O95968 | ||||
| TrEMBL | |||||
| UniProt Splice Variant | |||||
| Entrez Gene | 10648 | ||||
| UniGene | Hs.202686 | ||||
| RefSeq | NM_006552 | ||||
| HUGO | HGNC:18395 | ||||
| OMIM | 615060 | ||||
| CCDS | CCDS8015 | ||||
| HPRD | |||||
| IMGT | |||||
| EMBL | AJ224171 BC062693 BC069170 BC069289 | ||||
| GenPept | AAH62693 AAH69170 AAH69289 CAA11863 | ||||
| RNA Seq Atlas | 10648 | ||||