Version 5.4
Homo sapiens Gene: ACYP2
Summary
InnateDB Gene IDBG-51853.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ACYP2
Gene Name acylphosphatase 2, muscle type
Synonyms ACYM; ACYP
Species Homo sapiens
Ensembl Gene ENSG00000170634
Encoded Proteins
IDBP-51855
acylphosphatase 2, muscle type
IDBP-241145
acylphosphatase 2, muscle type
IDBP-293366
acylphosphatase 2, muscle type
IDBP-810098
acylphosphatase 2, muscle type
IDBP-810083
acylphosphatase 2, muscle type
IDBP-810090
acylphosphatase 2, muscle type
IDBP-810099
acylphosphatase 2, muscle type
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Acylphosphatase can hydrolyze the phosphoenzyme intermediate of different membrane pumps, particularly the Ca2+/Mg2+-ATPase from sarcoplasmic reticulum of skeletal muscle. Two isoenzymes have been isolated, called muscle acylphosphatase and erythrocyte acylphosphatase on the basis of their tissue localization. This gene encodes the muscle-type isoform (MT). An increase of the MT isoform is associated with muscle differentiation. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 2:53970838-54305300
Strand Forward strand
Band p16.2
Transcripts
ENST00000303536 ENSP00000306448
ENST00000394666 ENSP00000378161
ENST00000406041 ENSP00000385674
ENST00000494922 ENSP00000475312
ENST00000606082 ENSP00000475424
ENST00000607452 ENSP00000475986
ENST00000606865 ENSP00000475333
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
Experimentally validated
Total 4 [view]
Protein-Protein 3 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003998 acylphosphatase activity
Biological Process
GO:0006796 phosphate-containing compound metabolic process
GO:0008152 metabolic process
Cellular Component
GO:0005739 mitochondrion
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000060923
View Gene Order
ENSBTAG00000006852
Not yet available
Pathways
NETPATH
REACTOME
KEGG
hsa00620
Pyruvate metabolism pathway
INOH
INOH website
Pyruvate metabolism pathway
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene
RefSeq NM_138448
HUGO
OMIM
CCDS CCDS1850
HPRD
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca