Version 5.4
Homo sapiens Gene: RAB4B
Summary
InnateDB Gene IDBG-52197.7
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol RAB4B
Gene Name RAB4B, member RAS oncogene family
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000167578
Encoded Proteins
IDBP-52201
melanoma inhibitory activity
IDBP-52203
melanoma inhibitory activity
IDBP-762309
IDBP-762528
IDBP-765151
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary RAB proteins, such as RAB4B, are members of the RAS superfamily of small GTPases that are involved in vesicular trafficking (He et al., 2002 [PubMed 12450215]).[supplied by OMIM, Aug 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome 19:40778216-40796944
Strand Forward strand
Band q13.2
Transcripts
ENST00000378307 ENSP00000367557
ENST00000357052 ENSP00000349560
ENST00000600078
ENST00000602069
ENST00000595728 ENSP00000471803
ENST00000598430
ENST00000594800 ENSP00000470246
ENST00000597476
ENST00000602173 ENSP00000471504
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.
Experimentally validated
Total 6 [view]
Protein-Protein 2 [view]
Protein-DNA 4 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0003924 GTPase activity
GO:0005525 GTP binding
Biological Process
GO:0006184 GTP catabolic process
GO:0006886 intracellular protein transport
GO:0006913 nucleocytoplasmic transport
GO:0007165 signal transduction
GO:0007264 small GTPase mediated signal transduction
GO:0015031 protein transport
GO:0046323 glucose import
Cellular Component
GO:0005622 intracellular
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005886 plasma membrane
GO:0016020 membrane
GO:0032593 insulin-responsive compartment
GO:0048471 perinuclear region of cytoplasm
GO:0055037 recycling endosome
Orthologs
Species
Mus musculus
Gene ID
Gene Order
ENSMUSG00000053291
View Gene Order
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.672901
RefSeq NM_016154
HUGO
OMIM
CCDS CCDS33030
HPRD 11473
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca