Version 5.4
Homo sapiens Gene: SCGB3A2
Summary
InnateDB Gene IDBG-52299.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SCGB3A2
Gene Name secretoglobin, family 3A, member 2
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000164265
Encoded Proteins
IDBP-52301
secretoglobin, family 3A, member 2
IDBP-475579
secretoglobin, family 3A, member 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The protein encoded by this gene is a secreted lung surfactant protein and a downstream target of thyroid transcription factor. A single nucleotide polymorphism in the promoter of this gene results in susceptibility to asthma.[provided by RefSeq, Mar 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 5:147870682-147882191
Strand Forward strand
Band q32
Transcripts
ENST00000296694 ENSP00000296694
ENST00000504320 ENSP00000423930
ENST00000507160
ENST00000514688
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
Experimentally validated
Total 3 [view]
Protein-Protein 2 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
GO:0045087 innate immune response
Cellular Component
GO:0005576 extracellular region
GO:0071682 endocytic vesicle lumen
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000038791
View Gene Order
ENSBTAG00000004153
Not yet available
Pathways
NETPATH
REACTOME
REACT_160300
Binding and Uptake of Ligands by Scavenger Receptors pathway
REACT_163699
Scavenging by Class A Receptors pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.483765
RefSeq NM_054023
HUGO
OMIM
CCDS CCDS4287
HPRD 05940
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca