Version 5.4
Homo sapiens Gene: PLA2G16
Summary
InnateDB Gene IDBG-52540.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PLA2G16
Gene Name phospholipase A2, group XVI
Synonyms AdPLA; H-REV107-1; HRASLS3; HREV107; HREV107-1; HREV107-3; HRSL3
Species Homo sapiens
Ensembl Gene ENSG00000176485
Encoded Proteins
IDBP-52542
phospholipase A2, group XVI
IDBP-376746
phospholipase A2, group XVI
IDBP-587217
phospholipase A2, group XVI
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 11:63573195-63616883
Strand Reverse strand
Band q13.1
Transcripts
ENST00000323646 ENSP00000320337
ENST00000394613
ENST00000415826 ENSP00000389124
ENST00000540943 ENSP00000442576
ENST00000544269
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
Experimentally validated
Total 5 [view]
Protein-Protein 5 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004623 phospholipase A2 activity
GO:0005515 protein binding
GO:0008970 phosphatidylcholine 1-acylhydrolase activity
GO:0052739 phosphatidylserine 1-acylhydrolase activity
GO:0052740 1-acyl-2-lysophosphatidylserine acylhydrolase activity
Biological Process
GO:0006644 phospholipid metabolic process
GO:0008654 phospholipid biosynthetic process
GO:0016042 lipid catabolic process
GO:0036149 phosphatidylinositol acyl-chain remodeling
GO:0036150 phosphatidylserine acyl-chain remodeling
GO:0036151 phosphatidylcholine acyl-chain remodeling
GO:0036152 phosphatidylethanolamine acyl-chain remodeling
GO:0044281 small molecule metabolic process
GO:0045786 negative regulation of cell cycle
GO:0046474 glycerophospholipid biosynthetic process
Cellular Component
GO:0005575 cellular_component
GO:0005737 cytoplasm
GO:0005783 endoplasmic reticulum
GO:0005829 cytosol
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0048471 perinuclear region of cytoplasm
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000060675
View Gene Order
ENSBTAG00000015248
Not yet available
Pathways
NETPATH
REACTOME
REACT_120829
Acyl chain remodelling of PC pathway
REACT_120722
Acyl chain remodelling of PI pathway
REACT_121384
Acyl chain remodelling of PS pathway
REACT_121369
Acyl chain remodelling of PE pathway
REACT_22258
Metabolism of lipids and lipoproteins pathway
REACT_121401
Glycerophospholipid biosynthesis pathway
REACT_120870
Phospholipid metabolism pathway
REACT_111217
Metabolism pathway
KEGG
hsa00592
alpha-Linolenic acid metabolism pathway
hsa00590
Arachidonic acid metabolism pathway
hsa00564
Glycerophospholipid metabolism pathway
hsa00591
Linoleic acid metabolism pathway
hsa00565
Ether lipid metabolism pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.502775 Hs.619531
RefSeq NM_001128203 NM_007069
HUGO
OMIM
CCDS CCDS8047
HPRD 13671
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca