Version 5.4
Homo sapiens Gene: ATL3
Summary
InnateDB Gene IDBG-52583.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ATL3
Gene Name atlastin GTPase 3
Synonyms HSN1F
Species Homo sapiens
Ensembl Gene ENSG00000184743
Encoded Proteins
IDBP-232053
atlastin GTPase 3
IDBP-588519
atlastin GTPase 3
IDBP-588640
atlastin GTPase 3
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a member of a family of dynamin-like, integral membrane GTPases. The encoded protein is required for the proper formation of the network of interconnected tubules of the endoplasmic reticulum. Mutations in this gene may be associated with hereditary sensory neuropathy type IF. Alternatively spliced transcript variants that encode distinct isoforms have been described. [provided by RefSeq, Feb 2014]
Gene Information
Type Protein coding
Genomic Location Chromosome 11:63624087-63671921
Strand Reverse strand
Band q13.1
Transcripts
ENST00000398868 ENSP00000381844
ENST00000538786 ENSP00000437593
ENST00000540699 ENSP00000441842
ENST00000535789
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.
Experimentally validated
Total 6 [view]
Protein-Protein 6 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003924 GTPase activity
GO:0005525 GTP binding
GO:0042802 identical protein binding
Biological Process
GO:0006184 GTP catabolic process
GO:0007029 endoplasmic reticulum organization
GO:0007030 Golgi organization
GO:0051260 protein homooligomerization
Cellular Component
GO:0005783 endoplasmic reticulum
GO:0005789 endoplasmic reticulum membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000024759
View Gene Order
ENSBTAG00000003330
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.356719 Hs.627126 Hs.628708
RefSeq NM_001290048 NM_015459 XM_005273891
HUGO
OMIM
CCDS CCDS41663 CCDS73309
HPRD 13170
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca