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InnateDB Gene
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IDBG-52623.6
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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NBR2
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Gene Name
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neighbor of BRCA1 gene 2 (non-protein coding)
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Synonyms
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NCRNA00192
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Species
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Homo sapiens
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Ensembl Gene
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ENSG00000198496
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Encoded Proteins
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Protein Structure
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Useful resources
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Stemformatics
EHFPI
ImmGen
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| Summary |
This gene was identified by its close proximity on chromosome 17 to tumor suppressor gene BRCA1. Experimental evidence indicates that the two genes share a bi-directional promoter. Transcription for either gene is controlled individually by distinct transcriptional repressor factors. A short (112 amino acid) open reading frame is observed which includes a region derived from a LINE1 element. A strong Kozak signal is not observed for the putative ORF and the stop codon is more than 55 bases upstream of the last splice site for the transcript suggesting that the transcript is subject to nonsense-mediated decay. Therefore, this gene does not appear to encode a protein. [provided by RefSeq, Jul 2008]
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| Type |
transcribed_unprocessed_pseudogene
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Genomic Location
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Chromosome 17:43125610-43153671
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Strand
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Forward strand
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Band
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q21.31
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Transcripts
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Number of Interactions
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This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
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No orthologs found for this gene |
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SwissProt
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TrEMBL
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UniProt Splice Variant
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Entrez Gene
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UniGene
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RefSeq
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HUGO
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OMIM
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CCDS
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| HPRD |
10115
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IMGT
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EMBL
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GenPept
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RNA Seq Atlas
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Version 5.4