Version 5.4
Homo sapiens Gene: PEX13
Summary
InnateDB Gene IDBG-53182.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PEX13
Gene Name peroxisomal biogenesis factor 13
Synonyms NALD; PBD11A; PBD11B; ZWS
Species Homo sapiens
Ensembl Gene ENSG00000162928
Encoded Proteins
IDBP-53184
peroxisomal biogenesis factor 13
IDBP-293137
peroxisomal biogenesis factor 13
IDBP-377007
peroxisomal biogenesis factor 13
IDBP-377009
peroxisomal biogenesis factor 13
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a peroxisomal membrane protein that binds the type 1 peroxisomal targeting signal receptor via a SH3 domain located in the cytoplasm. Mutations and deficiencies in peroxisomal protein importing and peroxisome assembly lead to peroxisomal biogenesis disorders, an example of which is Zellweger syndrome. [provided by RefSeq, Oct 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 2:61017225-61051990
Strand Forward strand
Band p15
Transcripts
ENST00000295030 ENSP00000295030
ENST00000401576 ENSP00000384738
ENST00000414712 ENSP00000405413
ENST00000444100 ENSP00000405184
ENST00000472678
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 13 experimentally validated interaction(s) in this database.
Experimentally validated
Total 13 [view]
Protein-Protein 11 [view]
Protein-DNA 2 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0001561 fatty acid alpha-oxidation
GO:0001764 neuron migration
GO:0001967 suckling behavior
GO:0007626 locomotory behavior
GO:0016560 protein import into peroxisome matrix, docking
GO:0021795 cerebral cortex cell migration
GO:0060152 microtubule-based peroxisome localization
Cellular Component
GO:0005777 peroxisome
GO:0005778 peroxisomal membrane
GO:0005779 integral component of peroxisomal membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000020283
View Gene Order
ENSBTAG00000005257
Not yet available
Pathways
NETPATH
REACTOME
KEGG
hsa04146
Peroxisome pathway
INOH
PID NCI
Cross-References
SwissProt Q92968
TrEMBL
UniProt Splice Variant
Entrez Gene 5194
UniGene Hs.161377 Hs.601971
RefSeq NM_002618
HUGO HGNC:8855
OMIM 601789
CCDS CCDS1866
HPRD 03475
IMGT
EMBL AB022192 AF048755 AK315244 BC067090 CH471053 U71374
GenPept AAC39844 AAD05572 AAH67090 BAA88907 BAG37668 EAX00018
RNA Seq Atlas 5194

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca