Version 5.4
Homo sapiens Gene: ADPRHL1
Summary
InnateDB Gene IDBG-53232.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ADPRHL1
Gene Name ADP-ribosylhydrolase like 1
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000153531
Encoded Proteins
IDBP-53234
ADP-ribosylhydrolase like 1
IDBP-53236
ADP-ribosylhydrolase like 1
IDBP-374323
ADP-ribosylhydrolase like 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary ADP-ribosylation is a reversible posttranslational modification used to regulate protein function. ADP-ribosyltransferases (see ART1; MIM 601625) transfer ADP-ribose from NAD+ to the target protein, and ADP-ribosylhydrolases, such as ADPRHL1, reverse the reaction (Glowacki et al., 2002 [PubMed 12070318]).[supplied by OMIM, Mar 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 13:113421940-113453524
Strand Reverse strand
Band q34
Transcripts
ENST00000375418 ENSP00000364567
ENST00000356501 ENSP00000348894
ENST00000413169 ENSP00000416213
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 0
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0000287 magnesium ion binding
GO:0003875 ADP-ribosylarginine hydrolase activity
Biological Process
GO:0051725 protein de-ADP-ribosylation
Cellular Component
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000031448
View Gene Order
ENSBTAG00000020928
Not yet available
Cross-References
SwissProt Q8NDY3
TrEMBL X6RL45
UniProt Splice Variant
Entrez Gene 113622
UniGene Hs.606232 Hs.98669
RefSeq NM_138430 NM_199162
HUGO HGNC:21303
OMIM 610620
CCDS CCDS9535 CCDS9536
HPRD
IMGT
EMBL AJ313429 AL160251 BC009755
GenPept AAH09755 CAC86114 CAI39433 CAI39434 CAI39435
RNA Seq Atlas 113622

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca