Version 5.4
Homo sapiens Gene: MAGEB6
Summary
InnateDB Gene IDBG-53378.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol MAGEB6
Gene Name melanoma antigen family B, 6
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000176746
Encoded Proteins
IDBP-53380
melanoma antigen family B, 6
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene is a member of the MAGEB gene family. The members of this family have their entire coding sequences located in the last exon, and the encoded proteins show 50 to 68% sequence identity to each other. The promoters and first exons of the MAGEB genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. This gene is expressed in testis, and in a significant fraction of tumors of various histological types. The MAGEB genes are clustered on chromosome Xp22-p21. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome X:26192440-26195646
Strand Forward strand
Band p21.3
Transcripts
ENST00000379034 ENSP00000368320
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0005515 protein binding
Biological Process
GO:0008150 biological_process
Cellular Component
GO:0005575 cellular_component
Orthologs
No orthologs found for this gene
Cross-References
SwissProt Q8N7X4
TrEMBL
UniProt Splice Variant
Entrez Gene 158809
UniGene Hs.376011
RefSeq NM_173523
HUGO HGNC:23796
OMIM 300467
CCDS CCDS14217
HPRD
IMGT
EMBL AF320514 AK097561 BC067286 BC074920
GenPept AAG48624 AAH67286 AAH74920 BAC05102
RNA Seq Atlas 158809

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca