Version 5.4
Homo sapiens Gene: OMP
Summary
InnateDB Gene IDBG-544636.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol OMP
Gene Name olfactory marker protein
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000254550
Encoded Proteins
IDBP-593500
olfactory marker protein
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Olfactory marker protein is uniquely associated with the mature olfactory receptor neurons in many vertebrate species from fish to man. The OMP gene structure and protein sequence are highly conserved between mouse, rat and human. Results of the mouse knockout studies show that OMP-null mice are compromised in their ability to respond to odor stimuli, and that OMP represents a novel modulatory component of the odor detection/signal transduction cascade. [provided by RefSeq, Jul 2008]
Olfactory marker protein is uniquely associated with the mature olfactory receptor neurons in many vertebrate species from fish to man. The OMP gene structure and protein sequence are highly conserved between mouse, rat and human. Results of the mouse knockout studies show that OMP-null mice are compromised in their ability to respond to odor stimuli, and that OMP represents a novel modulatory component of the odor detection/signal transduction cascade. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 11:77102840-77103331
Strand Forward strand
Band q13.5
Transcripts
ENST00000529803 ENSP00000436376
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004871 signal transducer activity
Biological Process
GO:0007165 signal transduction
GO:0007268 synaptic transmission
GO:0007608 sensory perception of smell
GO:0022008 neurogenesis
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0030424 axon
GO:0043025 neuronal cell body
Orthologs
Species
Mus musculus
Gene ID
Gene Order
ENSMUSG00000074006
View Gene Order
Cross-References
SwissProt P47874
TrEMBL
UniProt Splice Variant
Entrez Gene 4975
UniGene Hs.673853
RefSeq NM_006189
HUGO HGNC:8136
OMIM 164340
CCDS CCDS53682
HPRD
IMGT
EMBL BC069115 BC069365 U01212
GenPept AAA20485 AAH69115 AAH69365
RNA Seq Atlas 4975

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca