Version 5.4
Homo sapiens Gene: RASD2
Summary
InnateDB Gene IDBG-5468.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol RASD2
Gene Name RASD family, member 2
Synonyms MGC:4834; Rhes; TEM2
Species Homo sapiens
Ensembl Gene ENSG00000100302
Encoded Proteins
IDBP-5470
RASD family, member 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a Ras-related protein that enriched in striatum. The product of this gene binds to GTP and possesses intrinsic GTPase activity. The gene belongs to the Ras superfamily of small GTPases. The exact function of this gene is unknown, but most striatum-specific mRNAs characterized to date encode components of signal transduction cascades. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 22:35540868-35554001
Strand Forward strand
Band q12.3
Transcripts
ENST00000216127 ENSP00000216127
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 15 experimentally validated interaction(s) in this database.
Experimentally validated
Total 15 [view]
Protein-Protein 15 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003924 GTPase activity
GO:0005515 protein binding
GO:0005525 GTP binding
GO:0031624 ubiquitin conjugating enzyme binding
GO:0031681 G-protein beta-subunit binding
Biological Process
GO:0001963 synaptic transmission, dopaminergic
GO:0006184 GTP catabolic process
GO:0006886 intracellular protein transport
GO:0006913 nucleocytoplasmic transport
GO:0007165 signal transduction
GO:0007264 small GTPase mediated signal transduction
GO:0007626 locomotory behavior
GO:0015031 protein transport
GO:0031397 negative regulation of protein ubiquitination
GO:0033235 positive regulation of protein sumoylation
GO:0043949 regulation of cAMP-mediated signaling
GO:0051897 positive regulation of protein kinase B signaling
Cellular Component
GO:0005622 intracellular
GO:0005886 plasma membrane
GO:0016020 membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000034472
View Gene Order
ENSBTAG00000017116
Not yet available
Cross-References
SwissProt Q96D21
TrEMBL
UniProt Splice Variant
Entrez Gene 23551
UniGene Hs.474711
RefSeq NM_014310 XM_005261441 XM_005261442 XM_005261443
HUGO HGNC:18229
OMIM 612842
CCDS CCDS13916
HPRD
IMGT
EMBL AF279143 AL022334 BC013419 CR456477
GenPept AAG00868 AAH13419 CAG30363 CAI21838
RNA Seq Atlas 23551

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca