Version 5.4
Homo sapiens Gene: HEXIM1
Summary
InnateDB Gene IDBG-54699.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol HEXIM1
Gene Name hexamethylene bis-acetamide inducible 1
Synonyms CLP1; EDG1; HIS1; MAQ1
Species Homo sapiens
Ensembl Gene ENSG00000186834
Encoded Proteins
IDBP-54701
hexamethylene bis-acetamide inducible 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Expression of this gene is induced by hexamethylene-bis-acetamide in vascular smooth muscle cells. This gene has no introns. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 17:45148502-45152101
Strand Forward strand
Band q21.31
Transcripts
ENST00000332499 ENSP00000328773
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 41 experimentally validated interaction(s) in this database.
Experimentally validated
Total 41 [view]
Protein-Protein 38 [view]
Protein-DNA 2 [view]
Protein-RNA 1 [view]
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity
GO:0005515 protein binding
GO:0017069 snRNA binding
Biological Process
GO:0000122 negative regulation of transcription from RNA polymerase II promoter
GO:0006351 transcription, DNA-templated
GO:0007507 heart development
GO:0045736 negative regulation of cyclin-dependent protein serine/threonine kinase activity
GO:0045892 negative regulation of transcription, DNA-templated
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000048878
View Gene Order
ENSBTAG00000006056
Not yet available
Cross-References
SwissProt O94992
TrEMBL
UniProt Splice Variant
Entrez Gene 10614
UniGene Hs.15299 Hs.721186 Hs.741758
RefSeq NM_006460
HUGO HGNC:24953
OMIM 607328
CCDS CCDS11495
HPRD
IMGT
EMBL AB021179 AK313557 BC006460
GenPept AAH06460 BAA36166 BAG36332
RNA Seq Atlas 10614

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca