Version 5.4
Homo sapiens Gene: PRSS58
Summary
InnateDB Gene IDBG-546993.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PRSS58
Gene Name protease, serine, 58
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000258223
Encoded Proteins
IDBP-587482
protease, serine, 58
IDBP-594017
protease, serine, 58
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a member of the trypsin family of serine proteases. This gene and several related trypsinogen genes are localized to the T cell receptor beta locus on chromosome 7. This gene was previously described as a trypsinogen-like pseudogene, but it is now thought to be a protein-coding gene. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 7:142252143-142258058
Strand Reverse strand
Band q34
Transcripts
ENST00000547058 ENSP00000447588
ENST00000552471 ENSP00000446916
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0003824 catalytic activity
GO:0004252 serine-type endopeptidase activity
Biological Process
GO:0006508 proteolysis
Cellular Component
GO:0005576 extracellular region
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000051936
View Gene Order
ENSBTAG00000003628
Not yet available
Cross-References
SwissProt Q8IYP2
TrEMBL
UniProt Splice Variant
Entrez Gene 136541
UniGene Hs.98609
RefSeq NM_001001317
HUGO HGNC:39125
OMIM
CCDS CCDS5871
HPRD 15572
IMGT
EMBL AK122940 AY358487 BC035384 CH236959 CH471198 DQ384426 DQ384427 DQ384428 DQ384429 DQ384431
GenPept AAH35384 AAQ88851 ABD48876 ABD48877 ABD48878 ABD48879 ABD48880 BAG53808 EAL23772 EAW51980 EAW51981
RNA Seq Atlas 136541

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca