Version 5.4
Homo sapiens Gene: FLRT3
Summary
InnateDB Gene IDBG-55228.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol FLRT3
Gene Name fibronectin leucine rich transmembrane protein 3
Synonyms HH21
Species Homo sapiens
Ensembl Gene ENSG00000125848
Encoded Proteins
IDBP-55230
fibronectin leucine rich transmembrane protein 3
IDBP-55232
fibronectin leucine rich transmembrane protein 3
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a member of the fibronectin leucine rich transmembrane protein (FLRT) family. FLRTs may function in cell adhesion and/or receptor signalling. Their protein structures resemble small leucine-rich proteoglycans found in the extracellular matrix. This gene is expressed in many tissues. Two alternatively spliced transcript variants encoding the same protein have been described for this gene. [provided by RefSeq, Jul 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 20:14322988-14337616
Strand Reverse strand
Band p12.1
Transcripts
ENST00000378053 ENSP00000367292
ENST00000341420 ENSP00000339912
ENST00000462077
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0005057 receptor signaling protein activity
GO:0005515 protein binding
GO:0030674 protein binding, bridging
GO:0045499 chemorepellent activity
Biological Process
GO:0007155 cell adhesion
GO:0007411 axon guidance
GO:0008150 biological_process
GO:0035556 intracellular signal transduction
GO:0050919 negative chemotaxis
Cellular Component
GO:0005578 proteinaceous extracellular matrix
GO:0005615 extracellular space
GO:0005887 integral component of plasma membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000051379
View Gene Order
ENSBTAG00000003319
Not yet available
Cross-References
SwissProt Q9NZU0
TrEMBL
UniProt Splice Variant
Entrez Gene 23767
UniGene Hs.41296 Hs.662712 Hs.686279
RefSeq NM_198391 NM_013281
HUGO HGNC:3762
OMIM 604808
CCDS CCDS13121
HPRD 05313
IMGT
EMBL AB040902 AF169677 AK027297 AK027670 AK027694 AK074909 AL132826 AY358319 BC020870 CH471133
GenPept AAF28461 AAH20870 AAQ88685 BAA95993 BAB55023 BAB55282 BAB55303 BAC11284 CAB86687 EAX10300 EAX10301
RNA Seq Atlas 23767

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca