Version 5.4
Homo sapiens Gene: ASCL4
Summary
InnateDB Gene IDBG-55236.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ASCL4
Gene Name achaete-scute complex homolog 4 (Drosophila)
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000187855
Encoded Proteins
IDBP-55238
achaete-scute complex homolog 4 (Drosophila)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Basic helix-loop-helix transcription factors, such as ASCL4, are essential for the determination of cell fate and the development and differentiation of numerous tissues (Jonsson et al., 2004 [PubMed 15475265]).[supplied by OMIM, Mar 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 12:107774385-107776644
Strand Forward strand
Band q23.3
Transcripts
ENST00000342331 ENSP00000345420
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0046983 protein dimerization activity
Biological Process
GO:0006351 transcription, DNA-templated
GO:0006357 regulation of transcription from RNA polymerase II promoter
GO:0043588 skin development
Cellular Component
GO:0005575 cellular_component
GO:0005634 nucleus
Orthologs
No orthologs found for this gene
Cross-References
SwissProt Q6XD76
TrEMBL
UniProt Splice Variant
Entrez Gene 121549
UniGene Hs.149910
RefSeq NM_203436
HUGO HGNC:24311
OMIM 609155
CCDS CCDS31894
HPRD
IMGT
EMBL AC007622 AY238895 BC128211 BC128212 BK000275
GenPept AAI28212 AAI28213 AAP69222 DAA01055
RNA Seq Atlas 121549

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca