Homo sapiens Gene: RRBP1 | |||||||||||||||||||
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Summary | |||||||||||||||||||
InnateDB Gene | IDBG-56137.6 | ||||||||||||||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||||||||
Gene Symbol | RRBP1 | ||||||||||||||||||
Gene Name | ribosome binding protein 1 homolog 180kDa (dog) | ||||||||||||||||||
Synonyms | ES/130; ES130; hES; RRp | ||||||||||||||||||
Species | Homo sapiens | ||||||||||||||||||
Ensembl Gene | ENSG00000125844 | ||||||||||||||||||
Encoded Proteins |
ribosome binding protein 1 homolog 180kDa (dog)
ribosome binding protein 1 homolog 180kDa (dog)
ribosome binding protein 1 homolog 180kDa (dog)
ribosome binding protein 1 homolog 180kDa (dog)
ribosome binding protein 1 homolog 180kDa (dog)
ribosome binding protein 1 homolog 180kDa (dog)
ribosome binding protein 1
ribosome binding protein 1
ribosome binding protein 1
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Protein Structure | |||||||||||||||||||
Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||||||||
Entrez Gene | |||||||||||||||||||
Summary |
This gene encodes a ribosome-binding protein of the endoplasmic reticulum (ER) membrane. Studies suggest that this gene plays a role in ER proliferation, secretory pathways and secretory cell differentiation, and mediation of ER-microtubule interactions. Alternative splicing has been observed and protein isoforms are characterized by regions of N-terminal decapeptide and C-terminal heptad repeats. Splicing of the tandem repeats results in variations in ribosome-binding affinity and secretory function. The full-length nature of variants which differ in repeat length has not been determined. Pseudogenes of this gene have been identified on chromosomes 3 and 7, and RRBP1 has been excluded as a candidate gene in the cause of Alagille syndrome, the result of a mutation in a nearby gene on chromosome 20p12. [provided by RefSeq, Apr 2012] |
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Gene Information | |||||||||||||||||||
Type | Protein coding | ||||||||||||||||||
Genomic Location | Chromosome 20:17613678-17682295 | ||||||||||||||||||
Strand | Reverse strand | ||||||||||||||||||
Band | p12.1 | ||||||||||||||||||
Transcripts | |||||||||||||||||||
Interactions | |||||||||||||||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 38 experimentally validated interaction(s) in this database.
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Gene Ontology | |||||||||||||||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Orthologs | |||||||||||||||||||
Species
Mus musculus
Bos taurus
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Gene ID
Gene Order
Not yet available
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Pathways | |||||||||||||||||||
NETPATH | |||||||||||||||||||
REACTOME | |||||||||||||||||||
KEGG |
Protein processing in endoplasmic reticulum pathway
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INOH | |||||||||||||||||||
PID NCI | |||||||||||||||||||
Cross-References | |||||||||||||||||||
SwissProt | |||||||||||||||||||
TrEMBL | |||||||||||||||||||
UniProt Splice Variant | |||||||||||||||||||
Entrez Gene | |||||||||||||||||||
UniGene | Hs.706335 | ||||||||||||||||||
RefSeq | NM_001042576 NM_004587 | ||||||||||||||||||
HUGO | |||||||||||||||||||
OMIM | |||||||||||||||||||
CCDS | CCDS13128 | ||||||||||||||||||
HPRD | 11796 | ||||||||||||||||||
IMGT | |||||||||||||||||||
EMBL | |||||||||||||||||||
GenPept | |||||||||||||||||||
RNA Seq Atlas | |||||||||||||||||||