Version 5.4
Homo sapiens Gene: EGR4
Summary
InnateDB Gene IDBG-56501.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol EGR4
Gene Name early growth response 4
Synonyms NGFI-C; NGFIC; PAT133
Species Homo sapiens
Ensembl Gene ENSG00000135625
Encoded Proteins
IDBP-474748
early growth response 4
IDBP-589824
early growth response 4
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 2:73290929-73293705
Strand Reverse strand
Band p13.2
Transcripts
ENST00000436467 ENSP00000419687
ENST00000545030 ENSP00000445626
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.
Experimentally validated
Total 6 [view]
Protein-Protein 4 [view]
Protein-DNA 2 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0046872 metal ion binding
Biological Process
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0008284 positive regulation of cell proliferation
GO:0043066 negative regulation of apoptotic process
GO:0071320 cellular response to cAMP
GO:0071371 cellular response to gonadotropin stimulus
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000071341
View Gene Order
ENSBTAG00000024058
Not yet available
Pathways
NETPATH
REACTOME
KEGG
INOH
PID NCI
cd8tcrdownstreampathway
Downstream signaling in naïve CD8+ T cells
nfat_tfpathway
Calcineurin-regulated NFAT-dependent transcription in lymphocytes
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.3052
RefSeq NM_001965
HUGO
OMIM
CCDS CCDS1925
HPRD 00550
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca