Version 5.4
Homo sapiens Gene: COPZ2
Summary
InnateDB Gene IDBG-56512.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol COPZ2
Gene Name coatomer protein complex, subunit zeta 2
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000005243
Encoded Proteins
IDBP-757675
IDBP-760543
IDBP-764813
IDBP-764694
IDBP-759625
IDBP-764104
IDBP-807369
coatomer protein complex, subunit zeta 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a subunit of the coatomer protein complex, a seven-subunit complex that functions in the formation of COPI-type, non-clathrin-coated vesicles. COPI vesicles function in the retrograde Golgi-to-ER transport of dilysine-tagged proteins. This gene is similar to a related family member, and the two encoded proteins form distinct isotypes of the coatomer protein complex. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 17:48026167-48038030
Strand Reverse strand
Band q21.32
Transcripts
ENST00000581637 ENSP00000463687
ENST00000584955 ENSP00000464484
ENST00000583414 ENSP00000463413
ENST00000580409
ENST00000579263 ENSP00000463841
ENST00000580174 ENSP00000463581
ENST00000581756 ENSP00000462035
ENST00000585182
ENST00000621465 ENSP00000480707
ENST00000612370
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
Experimentally validated
Total 4 [view]
Protein-Protein 3 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
GO:0006810 transport
GO:0006886 intracellular protein transport
GO:0015031 protein transport
GO:0016192 vesicle-mediated transport
Cellular Component
GO:0005801 cis-Golgi network
GO:0030126 COPI vesicle coat
GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000018672
View Gene Order
ENSBTAG00000039954
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene 51226
UniGene Hs.408434
RefSeq NM_016429
HUGO HGNC:19356
OMIM 615526
CCDS CCDS74092
HPRD 16739
IMGT
EMBL
GenPept
RNA Seq Atlas 51226

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca