Version 5.4
Homo sapiens Gene: SEC23B
Summary
InnateDB Gene IDBG-57331.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SEC23B
Gene Name Sec23 homolog B (S. cerevisiae)
Synonyms CDA-II; CDAII; CDAN2; HEMPAS
Species Homo sapiens
Ensembl Gene ENSG00000101310
Encoded Proteins
IDBP-57333
Sec23 homolog B (S. cerevisiae)
IDBP-57337
Sec23 homolog B (S. cerevisiae)
IDBP-57339
Sec23 homolog B (S. cerevisiae)
IDBP-57341
Sec23 homolog B (S. cerevisiae)
IDBP-368147
Sec23 homolog B (S. cerevisiae)
IDBP-368209
Sec23 homolog B (S. cerevisiae)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The protein encoded by this gene is a member of the SEC23 subfamily of the SEC23/SEC24 family, which is involved in vesicle trafficking. The encoded protein has similarity to yeast Sec23p component of COPII. COPII is the coat protein complex responsible for vesicle budding from the ER. The function of this gene product has been implicated in cargo selection and concentration. Multiple alternatively spliced transcript variants have been identified in this gene. [provided by RefSeq, Feb 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 20:18507493-18561415
Strand Forward strand
Band p11.23
Transcripts
ENST00000336714 ENSP00000338844
ENST00000262544 ENSP00000262544
ENST00000377475 ENSP00000366695
ENST00000377465 ENSP00000366685
ENST00000450074 ENSP00000403971
ENST00000422877 ENSP00000409882
ENST00000474619
ENST00000494645
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 32 experimentally validated interaction(s) in this database.
Experimentally validated
Total 32 [view]
Protein-Protein 32 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0008270 zinc ion binding
Biological Process
GO:0006886 intracellular protein transport
GO:0006888 ER to Golgi vesicle-mediated transport
GO:0016192 vesicle-mediated transport
Cellular Component
GO:0000139 Golgi membrane
GO:0005789 endoplasmic reticulum membrane
GO:0012505 endomembrane system
GO:0016020 membrane
GO:0030127 COPII vesicle coat
GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane
GO:0043231 intracellular membrane-bounded organelle
GO:0048471 perinuclear region of cytoplasm
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000027429
View Gene Order
ENSBTAG00000018295
Not yet available
Pathways
NETPATH
REACTOME
KEGG
hsa04141
Protein processing in endoplasmic reticulum pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.369373
RefSeq NM_001172745 NM_001172746 NM_006363 NM_032985 NM_032986
HUGO
OMIM
CCDS CCDS13137
HPRD 11543
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca