Homo sapiens Gene: CTSW
Summary
InnateDB Gene IDBG-57946.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CTSW
Gene Name cathepsin W
Synonyms LYPN
Species Homo sapiens
Ensembl Gene ENSG00000172543
Encoded Proteins
cathepsin W
cathepsin W
cathepsin W
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The protein encoded by this gene, a member of the peptidase C1 family, is a cysteine proteinase that may have a specific function in the mechanism or regulation of T-cell cytolytic activity. The encoded protein is found associated with the membrane inside the endoplasmic reticulum of natural killer and cytotoxic T-cells. Expression of this gene is up-regulated by interleukin-2. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 11:65879809-65883741
Strand Forward strand
Band q13.1
Transcripts
ENST00000307886 ENSP00000311300
ENST00000524681
ENST00000528419 ENSP00000436568
ENST00000526034 ENSP00000434267
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0008234 cysteine-type peptidase activity
Biological Process
GO:0006508 proteolysis
GO:0006955 immune response
Cellular Component
GO:0016020 membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Not yet available
Pathways
NETPATH
REACTOME
KEGG
Lysosome pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.416848
RefSeq NM_001335
HUGO
OMIM
CCDS CCDS8117
HPRD 03840
IMGT
EMBL
GenPept
RNA Seq Atlas