Version 5.4
Homo sapiens Gene: GPR34
Summary
InnateDB Gene IDBG-58083.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol GPR34
Gene Name G protein-coupled receptor 34
Synonyms LYPSR1
Species Homo sapiens
Ensembl Gene ENSG00000171659
Encoded Proteins
IDBP-58085
G protein-coupled receptor 34
IDBP-58087
G protein-coupled receptor 34
IDBP-810246
G protein-coupled receptor 34
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary G protein-coupled receptors (GPCRs), such as GPR34, are integral membrane proteins containing 7 putative transmembrane domains (TMs). These proteins mediate signals to the interior of the cell via activation of heterotrimeric G proteins that in turn activate various effector proteins, ultimately resulting in a physiologic response.[supplied by OMIM, Apr 2006]
Gene Information
Type Protein coding
Genomic Location Chromosome X:41688973-41697277
Strand Forward strand
Band p11.4
Transcripts
ENST00000378142 ENSP00000367384
ENST00000378138 ENSP00000367378
ENST00000620846 ENSP00000480296
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0004930 G-protein coupled receptor activity
Biological Process
GO:0007186 G-protein coupled receptor signaling pathway
Cellular Component
GO:0005887 integral component of plasma membrane
GO:0016021 integral component of membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000040229
View Gene Order
ENSBTAG00000020144
Not yet available
Cross-References
SwissProt Q9UPC5
TrEMBL Q3SAH0 Q5VT14
UniProt Splice Variant
Entrez Gene 2857
UniGene
RefSeq NM_001097579 NM_005300 XM_005272597
HUGO HGNC:4490
OMIM 300241
CCDS CCDS14258
HPRD
IMGT
EMBL AF039686 AF118670 AK027780 BC020678 CH471141 DQ106398 DQ106401 DQ106402 JF810887
GenPept AAD17248 AAD50531 AAH20678 AAZ99227 AAZ99230 AAZ99231 AEP43754 BAB55362 EAW59396 EAW59397
RNA Seq Atlas 2857

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca