Version 5.4
Homo sapiens Gene: DNAH6
Summary
InnateDB Gene IDBG-58779.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol DNAH6
Gene Name dynein, axonemal, heavy chain 6
Synonyms Dnahc6; DNHL1; HL-2; HL2
Species Homo sapiens
Ensembl Gene ENSG00000115423
Encoded Proteins
IDBP-58781
dynein, axonemal, heavy chain 6
IDBP-58783
dynein, axonemal, heavy chain 6
IDBP-810854
dynein, axonemal, heavy chain 6
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Dyneins are microtubule-associated motor protein complexes composed of several heavy, light, and intermediate chains. Two major classes of dyneins, axonemal and cytoplasmic, have been identified. DNAH6 is an axonemal dynein heavy chain (DHC) (Vaughan et al., 1996 [PubMed 8812413]).[supplied by OMIM, Mar 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 2:84516455-84819589
Strand Forward strand
Band p11.2
Transcripts
ENST00000389394 ENSP00000374045
ENST00000237449 ENSP00000237449
ENST00000476689
ENST00000468661
ENST00000494025
ENST00000602588 ENSP00000473441
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003777 microtubule motor activity
GO:0005524 ATP binding
GO:0016887 ATPase activity
Biological Process
GO:0001539 cilium or flagellum-dependent cell motility
GO:0006200 ATP catabolic process
GO:0007018 microtubule-based movement
GO:0008152 metabolic process
Cellular Component
GO:0005858 axonemal dynein complex
GO:0005874 microtubule
GO:0030286 dynein complex
Orthologs
Species
Mus musculus
Gene ID
Gene Order
ENSMUSG00000052861
View Gene Order
Pathways
NETPATH
REACTOME
KEGG
hsa05016
Huntington's disease pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.249972
RefSeq NM_001370 XM_006711956
HUGO
OMIM
CCDS CCDS46348
HPRD
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca