Version 5.4
Homo sapiens Gene: COPB2
Summary
InnateDB Gene IDBG-58841.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol COPB2
Gene Name coatomer protein complex, subunit beta 2 (beta prime)
Synonyms beta\'-COP
Species Homo sapiens
Ensembl Gene ENSG00000184432
Encoded Proteins
IDBP-58843
coatomer protein complex, subunit beta 2 (beta prime)
IDBP-478812
coatomer protein complex, subunit beta 2 (beta prime)
IDBP-473967
coatomer protein complex, subunit beta 2 (beta prime)
IDBP-485324
coatomer protein complex, subunit beta 2 (beta prime)
IDBP-475239
coatomer protein complex, subunit beta 2 (beta prime)
IDBP-483451
coatomer protein complex, subunit beta 2 (beta prime)
IDBP-477357
coatomer protein complex, subunit beta 2 (beta prime)
IDBP-480473
coatomer protein complex, subunit beta 2 (beta prime)
IDBP-473411
coatomer protein complex, subunit beta 2 (beta prime)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The Golgi coatomer complex (see MIM 601924) constitutes the coat of nonclathrin-coated vesicles and is essential for Golgi budding and vesicular trafficking. It consists of 7 protein subunits, including COPB2.[supplied by OMIM, Jul 2002]
Gene Information
Type Protein coding
Genomic Location Chromosome 3:139355600-139389732
Strand Reverse strand
Band q23
Transcripts
ENST00000333188 ENSP00000329419
ENST00000503326 ENSP00000426682
ENST00000507777 ENSP00000422295
ENST00000502734
ENST00000512309 ENSP00000422917
ENST00000510181
ENST00000515006 ENSP00000423271
ENST00000512153 ENSP00000422547
ENST00000513274 ENSP00000424144
ENST00000512242 ENSP00000427185
ENST00000510491
ENST00000514508 ENSP00000422469
ENST00000504295
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 53 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Experimentally validated
Total 53 [view]
Protein-Protein 51 [view]
Protein-DNA 2 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005198 structural molecule activity
GO:0005515 protein binding
Biological Process
GO:0006886 intracellular protein transport
GO:0006890 retrograde vesicle-mediated transport, Golgi to ER
GO:0006891 intra-Golgi vesicle-mediated transport
GO:0016192 vesicle-mediated transport
GO:0048205 COPI coating of Golgi vesicle
GO:0061024 membrane organization
Cellular Component
GO:0005829 cytosol
GO:0030117 membrane coat
GO:0030126 COPI vesicle coat
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000032458
View Gene Order
ENSBTAG00000014843
Not yet available
Pathways
NETPATH
NetPath_9
TNFalpha pathway
REACTOME
REACT_11096
COPI Mediated Transport pathway
REACT_11208
Golgi to ER Retrograde Transport pathway
REACT_11123
Membrane Trafficking pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL D6R997 D6RBG7 D6RBZ7 D6RCL6
UniProt Splice Variant
Entrez Gene 9276
UniGene Hs.600506 Hs.681616
RefSeq NM_004766
HUGO HGNC:2232
OMIM 606990
CCDS CCDS3108
HPRD 06103
IMGT
EMBL AC024933
GenPept
RNA Seq Atlas 9276

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca