Version 5.4
Homo sapiens Gene: RIN1
Summary
InnateDB Gene IDBG-58865.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol RIN1
Gene Name Ras and Rab interactor 1
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000174791
Encoded Proteins
IDBP-58867
Ras and Rab interactor 1
IDBP-583157
Ras and Rab interactor 1
IDBP-599286
Ras and Rab interactor 1
IDBP-593223
Ras and Rab interactor 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 11:66330242-66336840
Strand Reverse strand
Band q13.2
Transcripts
ENST00000311320 ENSP00000310406
ENST00000526246
ENST00000534824 ENSP00000431550
ENST00000530056 ENSP00000432798
ENST00000524804
ENST00000530745 ENSP00000431185
ENST00000528006
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 25 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.
Experimentally validated
Total 25 [view]
Protein-Protein 25 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 6 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005096 GTPase activator activity
GO:0005515 protein binding
GO:0017016 Ras GTPase binding
Biological Process
GO:0006897 endocytosis
GO:0007165 signal transduction
GO:0007613 memory
GO:0008306 associative learning
GO:0031914 negative regulation of synaptic plasticity
GO:0043547 positive regulation of GTPase activity
Cellular Component
GO:0005737 cytoplasm
GO:0005856 cytoskeleton
GO:0005886 plasma membrane
GO:0030425 dendrite
GO:0043025 neuronal cell body
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000024883
View Gene Order
ENSBTAG00000017681
Not yet available
Pathways
NETPATH
NetPath_4
EGFR1 pathway
REACTOME
KEGG
INOH
PID NCI
erbb1_downstream_pathway
ErbB1 downstream signaling
ras_pathway
Regulation of Ras family activation
Cross-References
SwissProt Q13671
TrEMBL B4DW96 E9PMB8 E9PNR2
UniProt Splice Variant
Entrez Gene 9610
UniGene Hs.1030
RefSeq NM_004292
HUGO HGNC:18749
OMIM 605965
CCDS CCDS31614
HPRD
IMGT
EMBL AK301430 AP001107 BC014417 L36463
GenPept AAB67270 AAH14417 BAG62958
RNA Seq Atlas 9610

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca