Homo sapiens Gene: PHF16
Summary
InnateDB Gene IDBG-59451.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PHF16
Gene Name PHD finger protein 16
Synonyms JADE-3; PHF16
Species Homo sapiens
Ensembl Gene ENSG00000102221
Encoded Proteins
PHD finger protein 16
PHD finger protein 16
jade family PHD finger 3
jade family PHD finger 3
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene is part of a gene cluster on chromosome Xp11.23. The encoded protein contains a zinc finger motif often found in transcriptional regulators, however, its exact function is not known. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq, Jul 2008]
This gene encodes a member of a family of large proteins containing PHD (plant homeo domain)-type zinc fingers. The encoded protein may be associated in a nuclear complex that functions in histone H4 acetylation. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq, Aug 2013]
Gene Information
Type Protein coding
Genomic Location Chromosome X:46912276-47061242
Strand Forward strand
Band p11.3
Transcripts
ENST00000424392 ENSP00000391009
ENST00000455411 ENSP00000400584
ENST00000614628 ENSP00000481850
ENST00000611250 ENSP00000479377
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
Experimentally validated
Total 5 [view]
Protein-Protein 5 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0008270 zinc ion binding
Biological Process
GO:0043966 histone H3 acetylation
GO:0043981 histone H4-K5 acetylation
GO:0043982 histone H4-K8 acetylation
GO:0043983 histone H4-K12 acetylation
Cellular Component
GO:0000123 histone acetyltransferase complex
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Not yet available
Pathways
NETPATH
REACTOME
HATs acetylate histones pathway
Chromatin organization pathway
Chromatin modifying enzymes pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL F2Z2B6 F2Z3N8
UniProt Splice Variant
Entrez Gene 9767
UniGene Hs.371977
RefSeq NM_001077445 NM_014735
HUGO HGNC:22982
OMIM 300618
CCDS CCDS14271
HPRD 06675
IMGT
EMBL AL627143 Z83822
GenPept
RNA Seq Atlas 9767